Target Name: TYW1
NCBI ID: G55253
Other Name(s): TYW1_HUMAN | tRNA-yW-synthesizing protein | tRNA-yW synthesizing protein 1 homolog A | YPL207W | TRNA-yW synthesizing protein 1 homolog, transcript variant 1 | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 | OTTHUMP00000160137 | tRNA wybutosine-synthesizing protein 1 homolog | MGC23001 | Radical S-adenosyl methionine and flavodoxin domain-containing protein 1 | MGC60291 | TYW1 variant 1 | FLJ10900 | TYW1A | tRNA-yW synthesizing protein 1 homolog | radical S-adenosyl methionine and flavodoxin domains 1 | Radical S-adenosyl methionine and flavodoxin domains 1 | RSAFD1 | radical S-adenosyl methionine and flavodoxin domain-containing protein 1

TYW1: A Potential Drug Target and Biomarker for the Treatment of Inflammatory Diseases

The TYW1 protein is a member of the transforming growth factor-beta (TGF-β) family, which plays a crucial role in cell growth, differentiation, and inflammation. TGF-β signaling has been implicated in the development and progression of numerous inflammatory diseases, including autoimmune disorders, cancer, and fibrosis. The identification of TYW1 as a potential drug target and biomarker has significant implications for the development of new therapeutic approaches for these diseases.

The TGF-β Signaling Pathway

TGF-β is a cytoplasmic protein that plays a vital role in cell growth and development by regulating cell proliferation, differentiation, and survival. The TGF-β signaling pathway involves the binding of TGF-β proteins to its downstream effector, Smad, which triggers a series of downstream signaling pathways.

The TGF-β pathway is involved in the regulation of cell proliferation, which is critical for the development and progression of many diseases, including cancer, autoimmune disorders, and fibrosis. TGF-β signaling has been implicated in the regulation of cell differentiation, as well as the regulation of cell survival and angiogenesis.

TYW1: A Potential Drug Target

The identification of TYW1 as a potential drug target has significant implications for the treatment of inflammatory diseases. TGF-β signaling has been implicated in the development and progression of many inflammatory diseases, including autoimmune disorders, cancer, and fibrosis. The identification of TYW1 as a potential drug target has the potential to disrupt the TGF-β signaling pathway and improve the treatment outcomes for inflammatory diseases.

The TGF-β pathway is involved in the regulation of cell proliferation, which is critical for the development and progression of many diseases. TGF-β signaling has been implicated in the regulation of cell differentiation, as well as the regulation of cell survival and angiogenesis. The identification of TYW1 as a potential drug target has significant implications for the treatment of inflammatory diseases, as it may help to disrupt the TGF-β signaling pathway and improve the treatment outcomes.

The TGF-β pathway is involved in the regulation of cell adhesion, which is critical for the development and progression of many diseases, including cancer. The TGF-β pathway has been shown to play a role in the regulation of cell adhesion, as well as the regulation of cell migration and the formation of tissues. The identification of TYW1 as a potential drug target may have implications for the development of new therapeutic approaches for cancer and other inflammatory diseases.

The TGF-β pathway is involved in the regulation of inflammation, which is critical for the development and progression of many diseases, including autoimmune disorders and cancer. The TGF-β pathway has been shown to play a role in the regulation of inflammation, as well as the regulation of immune cell function. The identification of TYW1 as a potential drug target may have implications for the development of new therapeutic approaches for the treatment of autoimmune disorders and cancer.

The TGF-β pathway is involved in the regulation of cell survival, which is critical for the development and progression of many diseases, including cancer. The TGF-β pathway has been shown to play a role in the regulation of cell survival, as well as the regulation of cell cycle progression. The identification of TYW1 as a potential drug target may have implications for the development of new therapeutic approaches for the treatment of cancer.

The TGF-β pathway is involved in the regulation of angiogenesis, which is critical for the development and progression of many diseases, including cancer. The TGF-β pathway has been shown to play a role in the regulation of angiogenesis, as well as the regulation of vascular barrier formation. The identification of TYW1 as a potential drug target

Protein Name: TRNA-yW Synthesizing Protein 1 Homolog

Functions: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity)

More Common Targets

TYW1B | TYW3 | U2 small nuclear ribonucleoprotein auxiliary factor | U2AF1 | U2AF1L4 | U2AF2 | U2SURP | U3 small nucleolar ribonucleoprotein (U3 snoRNP) complex | U5 small nuclear ribonucleoprotein complex | U7 snRNP complex | UACA | UAP1 | UAP1L1 | UBA1 | UBA2 | UBA3 | UBA5 | UBA52 | UBA52P1 | UBA6 | UBA6-DT | UBA7 | UBAC1 | UBAC2 | UBAC2-AS1 | UBALD1 | UBALD2 | UBAP1 | UBAP1L | UBAP2 | UBAP2L | UBASH3A | UBASH3B | UBB | UBBP1 | UBBP2 | UBBP4 | UBC | UBD | UBDP1 | UBE2A | UBE2B | UBE2C | UBE2CP3 | UBE2CP4 | UBE2D1 | UBE2D2 | UBE2D3 | UBE2D3P1 | UBE2D4 | UBE2DNL | UBE2E1 | UBE2E2 | UBE2E3 | UBE2F | UBE2F-SCLY | UBE2FP1 | UBE2G1 | UBE2G2 | UBE2H | UBE2HP1 | UBE2I | UBE2J1 | UBE2J2 | UBE2K | UBE2L1 | UBE2L3 | UBE2L6 | UBE2M | UBE2MP1 | UBE2N | UBE2NL | UBE2O | UBE2Q1 | UBE2Q2 | UBE2Q2P1 | UBE2Q2P11 | UBE2Q2P13 | UBE2Q2P16 | UBE2Q2P2 | UBE2QL1 | UBE2R2 | UBE2R2-AS1 | UBE2S | UBE2T | UBE2U | UBE2V1 | UBE2V1P2 | UBE2V1P9 | UBE2V2 | UBE2V2P1 | UBE2W | UBE2Z | UBE3A | UBE3B | UBE3C | UBE3D | UBE4A | UBE4B | UBFD1