PCDHA7: A Potential Drug Target and Biomarker (G56141)

Target Name: PCDHA7

NCBI ID: G56141

PCDHA7: A Potential Drug Target and Biomarker

P cadherin alpha 7 (PCDHA7) is a transmembrane protein that plays a crucial role in cell-cell adhesion. It is a member of the cadherin family, which is known for its role in cell-cell adhesion and tissue organization. CDHAs are involved in many physiological processes, including cell growth, differentiation, and tissue repair.

PCDHA7 is a 21-kDa protein that is expressed in many tissues, including epithelial, mesenchymal, and neural cells. It is involved in many different cellular processes, including cell adhesion, migration, and invasion. PCDHA7 has been shown to be involved in many diseases, including cancer, neurodegenerative diseases, and developmental disorders.

One of the key functions of PCDHA7 is its role in cell-cell adhesion. It is a critical protein for the formation of tight junctions, which are a type of cell-cell adhesion that helps to maintain tissue structure and prevent the excessive migration of cells. PCDHA7 is also involved in the regulation of cell signaling pathways, including the TGF-β pathway. This pathway is involved in many cellular processes, including cell growth, differentiation, and survival.

PCDHA7 has also been shown to be involved in the regulation of neurotransmitter release from neurons. Neurons that release neurotransmitters are important for many different functions in the nervous system, including movement, sensation, and communication. PCDHA7 has been shown to be involved in the regulation of neurotransmitter release from neurons, including the neurotransmitter serotonin.

In addition to its role in cell-cell adhesion and neurotransmission, PCDHA7 is also involved in the regulation of many other cellular processes. It is a critical protein for the regulation of cell signaling pathways, including the Wnt pathway. This pathway is involved in many cellular processes, including cell growth, differentiation, and survival. PCDHA7 is also involved in the regulation of cell adhesion, as well as the regulation of gene expression.

PCDHA7 has also been shown to be involved in the development and progression of many diseases. For example, PCDHA7 has been shown to be involved in the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. It is also involved in the development of cancer, including colon cancer. PCDHA7 has been shown to be involved in the regulation of many cellular processes that are important for tumor progression, including cell adhesion, angiogenesis, and metastasis.

In addition to its role in disease development, PCDHA7 is also a potential drug target. Many drugs that are currently in use to treat various diseases, including cancer and neurodegenerative diseases, target PCDHA7. For example, some drugs that are used to treat breast cancer target the PCDHA7 gene. Others that are used to treat neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, target PCDHA7 directly or indirectly.

In conclusion, PCDHA7 is a transmembrane protein that is involved in many cellular processes. It is a critical protein for the regulation of cell-cell adhesion and neurotransmission, as well as the regulation of many other cellular processes. In addition to its role in disease development, PCDHA7 is also a potential drug target. Further research is needed to fully understand the role of PCDHA7 in cellular processes and its potential as a drug target.

Protein Name: Protocadherin Alpha 7

Functions: Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination. Thereby, it is involved in the establishment and maintenance of specific neuronal connections in the brain

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