Target Name: PCED1A
NCBI ID: G64773
Other Name(s): Family with sequence similarity 113, member A | PC-esterase domain containing 1A | sarcoma antigen NY-SAR-23 | PC-esterase domain-containing protein 1A | family with sequence similarity 113, member A | C20orf81 | PC-esterase domain containing 1A, transcript variant 1 | Sarcoma antigen NY-SAR-23 | Protein FAM113A | PCED1A variant 1 | PC-esterase domain-containing protein 1A (isoform 1) | bA12M19.1 | PED1A_HUMAN | FAM113A

Understanding PCED1A: Potential Drug Target

PCED1A, also known as Family with Sequence Similarity 113 member A, is a protein that is expressed in various tissues of the body. It is a member of the superfamily of RNA-protein interactions and is involved in various cellular processes. One of the key functions of PCED1A is its role in the regulation of gene expression, which is critical for the development and maintenance of tissues and organs.

Drug Targeting

PCED1A has been identified as a potential drug target due to its involvement in various cellular processes. One of the main reasons for its potential as a drug target is its unique structure and the various functions that it plays in the body.

One of the key features of PCED1A is its nuclear localization. PCED1A is a nuclear protein, which means that it is primarily localized to the nucleus of the cell. This is important because it allows PCED1A to interact with other proteins that are also nuclear-localized . These interactions can modulate the activity of PCED1A and affect various cellular processes.

Another potential drug target for PCED1A is its role in the regulation of gene expression. PCED1A has been shown to play a role in the regulation of gene expression by binding to specific DNA sequences. This interaction between PCED1A and DNA can modulate the activity of gene transcription factors, which are responsible for transmitting genetic information from the DNA to the RNA molecule.

In addition to its role in gene expression, PCED1A is also involved in the regulation of cellular processes such as cell adhesion, migration and invasion. These functions are critical for the development and maintenance of tissues and organs, and therefore, modulating PCED1A activity could be a potential therapeutic approach for various diseases.

Another potential drug target for PCED1A is its role in the regulation of inflammation. PCED1A has been shown to play a role in the regulation of inflammation and its expression is often increased in tissues that are under inflammatory stress. This makes PCED1A an attractive target for anti -inflammatory therapies.

Expression and Measurement

PCED1A is a protein that is expressed in various tissues of the body, including muscle, heart, brain, and testes. Its expression level can be measured using various techniques such as qRT-PCR, western blotting, and immunofluorescence. These techniques allow researchers to quantify the amount of PCED1A protein in a given sample and to study its distribution and localization in different tissues.

It is important to note that the expression of PCED1A can be modulated by various factors, such as gene expression, DNA methylation, and histone modification. Therefore, it is important to study the regulation of PCED1A expression in different tissues and conditions to fully understand its role in cellular processes.

Conclusion

In conclusion, PCED1A is a protein that is involved in various cellular processes and has been identified as a potential drug target due to its unique structure and the various functions that it plays in the body. Its nuclear localization, regulation of gene expression and inflammation make it an attractive target for therapeutic approaches. Further research is needed to fully understand the regulation of PCED1A expression and its role in cellular processes, and to explore its potential as a drug target.

Protein Name: PC-esterase Domain Containing 1A

More Common Targets

PCED1B | PCED1B-AS1 | PCED1CP | PCF11 | PCF11-AS1 | PCGEM1 | PCGF1 | PCGF2 | PCGF3 | PCGF3-AS1 | PCGF5 | PCGF6 | PCID2 | PCIF1 | PCK1 | PCK2 | PCLAF | PCLO | PCM1 | PCMT1 | PCMTD1 | PCMTD1-DT | PCMTD2 | PCNA | PCNA-AS1 | PCNAP1 | PCNAP3 | PCNP | PCNPP1 | PCNT | PCNX1 | PCNX2 | PCNX3 | PCNX4 | PCOLCE | PCOLCE-AS1 | PCOLCE2 | PCOTH | PCP2 | PCP4 | PCP4L1 | PCSK1 | PCSK1N | PCSK2 | PCSK4 | PCSK5 | PCSK6 | PCSK6-AS1 | PCSK7 | PCSK9 | PCTP | PCYOX1 | PCYOX1L | PCYT1A | PCYT1B | PCYT2 | PDAP1 | PDC | PDCD1 | PDCD10 | PDCD11 | PDCD1LG2 | PDCD2 | PDCD2L | PDCD4 | PDCD4-AS1 | PDCD5 | PDCD6 | PDCD6IP | PDCD6IPP2 | PDCD6P1 | PDCD7 | PDCL | PDCL2 | PDCL3 | PDCL3P4 | PDCL3P6 | PDE10A | PDE11A | PDE11A-AS1 | PDE12 | PDE1A | PDE1B | PDE1C | PDE2A | PDE2A-AS1 | PDE3A | PDE3B | PDE4A | PDE4B | PDE4C | PDE4D | PDE4DIP | PDE5A | PDE6A | PDE6B | PDE6C | PDE6D | PDE6G | PDE6H