PDCD2L: A Potential Drug Target for Cell-Cell Adhesion, Survival and Inflammation

Target Name: PDCD2L

NCBI ID: G84306

PDCD2L: A Potential Drug Target for Cell-Cell Adhesion, Survival and Inflammation

PDCD2L, also known as MGC13096, is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the PDCD family, which includes PDCD1 and PDCD3, and is involved in the regulation of cell-cell adhesion and survival.

PDCD2L has been identified as a potential drug target due to its role in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its function as a protein that can modulate the interactions between cells has led to the idea that it may be a useful target for drugs that target cell-cell adhesion.

One of the key functions of PDCD2L is its role in cell-cell adhesion. Adhesion between cells is critical for many biological processes, including tissue repair and regeneration, and is also involved in the development and maintenance of tissues and organs. PDCD2L has been shown to play a role in regulating cell-cell adhesion by modulating the interactions between cells and the production of adhesion molecules.

PDCD2L has also been shown to be involved in the regulation of cell survival. Many diseases, including cancer, are characterized by the destruction of cells that are no longer able to divide and survive. PDCD2L has been shown to play a role in the regulation of cell survival by modulating the production of signaling molecules that promote cell growth and proliferation.

PDCD2L has also been shown to be involved in the regulation of inflammation. Inflammation is a critical immune response that helps the body to fight off infections and injuries, but can also lead to the development of diseases such as autoimmune disorders. PDCD2L has been shown to play a role in the regulation of inflammation by modulating the production of signaling molecules that promote inflammation.

PDCD2L has also been shown to be involved in the regulation of stem cell proliferation. Stem cells are a type of cell that have the ability to develop into any type of cell in the body, and are often used in the treatment of diseases such as cancer. PDCD2L has been shown to play a role in the regulation of stem cell proliferation by modulating the production of signaling molecules that promote stem cell growth and differentiation.

In conclusion, PDCD2L is a protein that is involved in several important functions in the regulation of cell-cell adhesion, survival, and inflammation. As a potential drug target, PDCD2L has the potential to be used to treat a wide range of diseases. Further research is needed to fully understand the role of PDCD2L in these processes and to develop effective treatments.

Protein Name: Programmed Cell Death 2 Like

Functions: Over-expression suppresses AP1, CREB, NFAT, and NF-kB transcriptional activation, and delays cell cycle progression at S phase

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