PDHA2: A Drug Target and Biomarker for Various Diseases (G5161)
PDHA2: A Drug Target and Biomarker for Various Diseases
PDHA2 (poly(D,A)nitrile), also known as PDP, is a drug target and a biomarker that is involved in the development and progression of various diseases, including cancer. It is a transmembrane protein that is expressed in various tissues and cells in the body.
PDHA2 is a key regulator of the cell-cell adhesion process, which is critical for the development and maintenance of tissues and organs. It plays a vital role in the regulation of cell proliferation, differentiation, and adhesion, as well as in the regulation of cell survival.
PDHA2 is also involved in the regulation of cell signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, and is a key factor in the development and progression of many diseases, including cancer.
PDHA2 is a good candidate for drug targeting because of its involvement in the regulation of cell signaling pathways and its role in the development and progression of various diseases. It is also a potential biomarker for the diagnosis and treatment of these diseases.
One of the main challenges in the development of new drugs is the difficulty of predicting the exact mechanism of action of a drug. This is because drugs can act on multiple targets, making it difficult to determine exactly how and where the drug works. PDHA2 is one of
Protein Name: Pyruvate Dehydrogenase E1 Subunit Alpha 2
Functions: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle
More Common Targets
PDHB | PDHX | PDIA2 | PDIA3 | PDIA3P1 | PDIA4 | PDIA5 | PDIA6 | PDIK1L | PDILT | PDK1 | PDK2 | PDK3 | PDK4 | PDLIM1 | PDLIM1P4 | PDLIM2 | PDLIM3 | PDLIM4 | PDLIM5 | PDLIM7 | PDP1 | PDP2 | PDPK1 | PDPK2P | PDPN | PDPR | PDPR2P | PDRG1 | PDS5A | PDS5B | PDS5B-DT | PDSS1 | PDSS2 | PDX1 | PDXDC1 | PDXDC2P-NPIPB14P | PDXK | PDXP | PDYN | PDYN-AS1 | PDZD11 | PDZD2 | PDZD4 | PDZD7 | PDZD8 | PDZD9 | PDZK1 | PDZK1IP1 | PDZK1P1 | PDZPH1P | PDZRN3 | PDZRN3-AS1 | PDZRN4 | PEA15 | PEAK1 | PEAK3 | PEAR1 | PeBoW complex | PEBP1 | PEBP1P2 | PEBP4 | PECAM1 | PECR | PEDS1 | PEDS1-UBE2V1 | PEF1 | PEG10 | PEG13 | PEG3 | PEG3-AS1 | PELATON | PELI1 | PELI2 | PELI3 | PELO | PELP1 | PELP1-DT | PEMT | PENK | PENK-AS1 | PEPD | Peptidyl arginine deiminase (PAD) | Peptidylprolyl Isomerase | PER1 | PER2 | PER3 | PER3P1 | PERM1 | Peroxiredoxin | Peroxisome Proliferator-Activated Receptors (PPAR) | PERP | PES1 | PET100 | PET117 | PEX1 | PEX10 | PEX11A | PEX11B | PEX11G