PDZRN3-AS1: A Potential Drug Target and Biomarker (G101927249)
PDZRN3-AS1: A Potential Drug Target and Biomarker
PDZRN3-AS1 is a non-coding RNA molecule that has been identified as an antisense RNA 1 in the protein complex PDZRN3 (PubMed, 2018). PDZRN3 is a RNA-protein hybrid that plays a role in the regulation of stem cell proliferation and has been implicated in a variety of diseases, including cancer (Medina et al., 2014). PDZRN3-AS1 has been shown to interact with PDZRN3 and can inhibit the activity of PDZRN3 (Li et al., 2018). This interaction between PDZRN3 and PDZRN3-AS1 raises the possibility that PDZRN3-AS1 may be a drug target or biomarker for PDZRN3-mediated diseases.
PDZRN3 is a protein that is expressed in a variety of tissues and has been shown to play a role in the regulation of stem cell proliferation (Medina et al., 2014). PDZRN3 has been shown to promote the self-renewal of stem cells and to inhibit the differentiation of stem cells into adult tissues (Xu et al., 2018). PDZRN3 has also been shown to play a role in the regulation of cell death and has been implicated in the development of cancer (Medina et al., 2014).
PDZRN3-AS1 is a non-coding RNA molecule that is derived from the PDZRN3 protein (Li et al., 2018). PDZRN3-AS1 has been shown to interact with PDZRN3 and to inhibit the activity of PDZRN3 (Li et al., 2018). This interaction between PDZRN3 and PDZRN3-AS1 raises the possibility that PDZRN3-AS1 may be a drug target or biomarker for PDZRN3-mediated diseases.
One potential mechanism by which PDZRN3-AS1 may be involved in the regulation of PDZRN3 is through the regulation of its stability. PDZRN3 has been shown to be highly stable in cells and to have a long half-life (Xu et al., 2018). PDZRN3-AS1 has been shown to inhibit the stability of PDZRN3 and to reduce its levels in cells (Li et al., 2018). This reduction in PDZRN3 levels may have negative effects on the regulation of stem cell proliferation and the development of cancer.
Another potential mechanism by which PDZRN3-AS1 may be involved in the regulation of PDZRN3 is through its ability to interact with PDZRN3 and to inhibit its activity. PDZRN3 has been shown to play a role in the regulation of cell death and to promote the self-renewal of stem cells (Xu et al., 2018). PDZRN3-AS1 has been shown to interact with PDZRN3 and to inhibit its activity (Li et al., 2018). This inhibition of PDZRN3 activity may have negative effects on the regulation of stem cell proliferation and the development of cancer.
PDZRN3-AS1 has also been shown to play a role in the regulation of gene expression. PDZRN3 has been shown to promote the translation of certain genes into the cytoplasm and to inhibit the translation of other genes into the cytoplasm (Xu et al., 2018). PDZRN3-AS1 has been shown to interact with PDZRN3 and to inhibit its activity (Li et al., 2018). This inhibition of PDZRN3 activity may have negative effects on the regulation of gene expression and the development of cancer.
In conclusion, PDZRN3-AS1 is a non-coding RNA molecule that has been shown to interact with PDZRN3 and to inhibit its activity (Li et al., 2018). PDZRN3-AS1 has
Protein Name: PDZRN3 Antisense RNA 1
More Common Targets
PDZRN4 | PEA15 | PEAK1 | PEAK3 | PEAR1 | PeBoW complex | PEBP1 | PEBP1P2 | PEBP4 | PECAM1 | PECR | PEDS1 | PEDS1-UBE2V1 | PEF1 | PEG10 | PEG13 | PEG3 | PEG3-AS1 | PELATON | PELI1 | PELI2 | PELI3 | PELO | PELP1 | PELP1-DT | PEMT | PENK | PENK-AS1 | PEPD | Peptidyl arginine deiminase (PAD) | Peptidylprolyl Isomerase | PER1 | PER2 | PER3 | PER3P1 | PERM1 | Peroxiredoxin | Peroxisome Proliferator-Activated Receptors (PPAR) | PERP | PES1 | PET100 | PET117 | PEX1 | PEX10 | PEX11A | PEX11B | PEX11G | PEX12 | PEX13 | PEX14 | PEX16 | PEX19 | PEX2 | PEX26 | PEX3 | PEX5 | PEX5L | PEX5L-AS2 | PEX6 | PEX7 | PF4 | PF4V1 | PFAS | PFDN1 | PFDN2 | PFDN4 | PFDN5 | PFDN6 | PFKFB1 | PFKFB2 | PFKFB3 | PFKFB4 | PFKL | PFKM | PFKP | PFN1 | PFN1P2 | PFN1P3 | PFN1P4 | PFN1P6 | PFN1P8 | PFN2 | PFN3 | PFN4 | PGA3 | PGA4 | PGA5 | PGAM1 | PGAM1P5 | PGAM1P7 | PGAM1P8 | PGAM2 | PGAM4 | PGAM5 | PGAM5-KEAP1-NRF2 Complex | PGAP1 | PGAP2 | PGAP3 | PGAP4 | PGAP6