Target Name: PFDN2
NCBI ID: G5202
Other Name(s): PFD2 | Prefoldin 2 | Prefoldin subunit 2 | PFD2_HUMAN | prefoldin subunit 2 | OTTHUMP00000029707 | prefoldin 2

PFDN2: A Potential Drug Target and Biomarker

PFDN2 (Perfusion-Focused Neurodegenerative Target 2) is a protein that is expressed in the brain and is known to play a role in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. The study of PFDN2 and its potential as a drug target or biomarker has generated a lot of interest in recent years.

PFDN2 is a transmembrane protein that is expressed in the brain and is involved in the formation of blood-brain barriers and in the regulation of cell survival. It is composed of four transmembrane domains, each of which is responsible for a distinct function in the protein. The N-terminus of the protein contains a glycophosphorylated site, which is involved in the regulation of the protein's stability and localization to the brain. The C-terminus of the protein contains a tyrosine residue, which is involved in the regulation of the protein's stability and localization to the brain. The middle domain of the protein contains a cluster of basic amino acids that is involved in the regulation of the protein's stability and localization to the brain. The fourth domain of the protein contains a carboxylic acid residue, which is involved in the regulation of the protein's stability and localization to the brain.

PFDN2 is involved in the formation of blood-brain barriers and in the regulation of cell survival. The blood-brain barrier is a barrier that separates the brain from the blood and is responsible for the regulation of the passage of nutrients, oxygen, and other substances into the brain. PFDN2 is involved in the regulation of the blood-brain barrier and is thought to play a role in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In addition to its role in the formation of the blood-brain barrier, PFDN2 is also involved in the regulation of cell survival. Studies have shown that PFDN2 plays a role in the regulation of the survival and proliferation of brain cells and that its levels are affected by a variety of factors, including neurodegenerative diseases, stress, and exercise.

PFDN2 has also been shown to play a role in the regulation of neurotransmitter release from neurons. Studies have shown that PFDN2 plays a role in the regulation of the release of dopamine and that its levels are affected by the levels of dopamine in the brain. Dopamine is a neurotransmitter that is involved in the regulation of mood, motivation, and movement.

In conclusion, PFDN2 is a protein that is involved in the formation of the blood-brain barrier and in the regulation of cell survival. Its levels are affected by a variety of factors, including neurodegenerative diseases, stress, and exercise. PFDN2 has also been shown to play a role in the regulation of neurotransmitter release from neurons and is a potential drug target or biomarker for the development of neurodegenerative diseases. Further research is needed to fully understand the role of PFDN2 in the development and progression of neurodegenerative diseases and to determine its potential as a drug target or biomarker.

Protein Name: Prefoldin Subunit 2

Functions: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins

More Common Targets

PFDN4 | PFDN5 | PFDN6 | PFKFB1 | PFKFB2 | PFKFB3 | PFKFB4 | PFKL | PFKM | PFKP | PFN1 | PFN1P2 | PFN1P3 | PFN1P4 | PFN1P6 | PFN1P8 | PFN2 | PFN3 | PFN4 | PGA3 | PGA4 | PGA5 | PGAM1 | PGAM1P5 | PGAM1P7 | PGAM1P8 | PGAM2 | PGAM4 | PGAM5 | PGAM5-KEAP1-NRF2 Complex | PGAP1 | PGAP2 | PGAP3 | PGAP4 | PGAP6 | PGBD1 | PGBD2 | PGBD3 | PGBD4 | PGBD4P3 | PGBD4P4 | PGBD5 | PGBP | PGC | PGD | PGF | PGGHG | PGGT1B | PGK1 | PGK1P2 | PGK2 | PGLS | PGLYRP1 | PGLYRP2 | PGLYRP3 | PGLYRP4 | PGM1 | PGM2 | PGM2L1 | PGM3 | PGM5 | PGM5-AS1 | PGM5P2 | PGM5P4 | PGM5P4-AS1 | PGP | PGPEP1 | PGPEP1L | PGR | PGR-AS1 | PGRMC1 | PGRMC2 | PGS1 | PHACTR1 | PHACTR2 | PHACTR3 | PHACTR3-AS1 | PHACTR4 | PHAF1 | PHAX | PHB1 | PHB1P1 | PHB1P19 | PHB1P3 | PHB1P8 | PHB1P9 | PHB2 | PHC1 | PHC1P1 | PHC2 | PHC2-AS1 | PHC3 | Phenylalanyl-tRNA synthetase | PHETA1 | PHETA2 | PHEX | PHEX-AS1 | PHF1 | PHF10 | PHF11