PHETA2 as A Potential Drug Target for Neurodegenerative Diseases

Target Name: PHETA2

NCBI ID: G150368

PHETA2 as A Potential Drug Target for Neurodegenerative Diseases

PHETA2 (Sesquipedalian-2) is a protein that is expressed in the brain and is known for its role in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. It is a member of the PHETA family of proteins, which are known for their ability to interact with various signaling molecules in the brain.

Recent studies have suggested that PHETA2 may be a drug target (or biomarker) for the treatment of neurodegenerative diseases. In particular, PHETA2 has been shown to be involved in the development of neurofibrillary tangles, which are a hallmark of Alzheimer's disease, and has been shown to interact with the protein tau.

PHETA2 has also been shown to interact with the protein beta-amyloid, which is a hallmark of Parkinson's disease. beta-amyloid is a protein that is derived from the neurotransmitter acetylcholine, which is a key component of the hallmark neurotransmitter neurotransmitter acetylcholine.

PHETA2 has been shown to interact with the protein N-methyl-D-aspartate (NMDA), which is a neurotransmitter that is involved in pain signaling and has been implicated in the development of neurodegenerative diseases.

In addition to its role in the development and progression of neurodegenerative diseases, PHETA2 has also been shown to have potential therapeutic applications in the treatment of other conditions. For example, PHETA2 has been shown to have anti-inflammatory properties and has been shown to interact with the protein interleukin-1 (IL-1). This suggests that PHETA2 may have potential as a therapeutic agent for the treatment of autoimmune diseases.

Overall, PHETA2 is a protein that has the potential to be a drug target (or biomarker) for the treatment of neurodegenerative diseases. Further research is needed to fully understand its role and to develop effective treatments for these conditions.

Protein Name: PH Domain Containing Endocytic Trafficking Adaptor 2

Functions: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane

More Common Targets