Target Name: PIANP
NCBI ID: G196500
Other Name(s): PILR alpha associated neural protein | PIANP variant 2 | PILR alpha-associated neural protein (isoform a) | C12orf53 | LEDA1 | PILR alpha-associated neural protein precursor | PANP | PILR alpha associated neural protein, transcript variant 1 | paired immunoglobin-like type 2 receptor-associating neural protein | PILR alpha-associated neural protein | PILR alpha-associated neural protein (isoform b) | PILR alpha associated neural protein, transcript variant 2 | PIANP variant 1 | PIANP_HUMAN | leda-1 | PILR-associating neural protein | Paired immunoglobin-like type 2 receptor-associating neural protein | liver endothelial differentiation-associated protein-1 | Liver endothelial differentiation-associated protein-1

PIANP: A Drug Target / Disease Biomarker

Pain is a fundamental human experience that is associated with significant morbidity and mortality. Chronic pain, in particular, can significantly impact an individual's quality of life and overall well-being. The painkiller market is one of the largest pharmaceutical markets in the world, with an estimated annual sales of over $300 billion. However, the current painkiller drugs that are available are often limited in their effectiveness and can have significant side effects. As a result, there is a growing need for new and innovative painkillers that can provide more effective and fewer side effects.

One potential drug that is being investigated as a pain target is PIANP (pronounced pi-anna). PIANP is a small protein that is expressed in the endoplasmic reticulum (ER) and has been shown to play a role in pain signaling. PIANP has been shown to interact with multiple pain signaling pathways, including the TRPV1 receptor, which is responsible for mediating pain signals.

In addition to its potential role in pain signaling, PIANP has also been shown to have potential as a drug target. PIANP has been shown to interact with several intracellular signaling pathways, including the PI3K/Akt signaling pathway. This pathway is involved in the regulation of cellular signaling, including the regulation of pain signaling. By targeting this pathway, PIANP has the potential to modulate pain signaling and provide effective pain relief.

PIANP has also been shown to interact with the GPR117 receptor, which is a potential drug target for chronic pain. The GPR117 receptor is involved in the regulation of pain signaling and has been shown to play a role in the development of chronic pain. PIANP has been shown to interact with GPR117, which could potentially modulate pain signaling and provide effective pain relief.

In conclusion, PIANP is a promising drug target for pain relief. Its interaction with multiple pain signaling pathways, including TRPV1 and GPR117, makes it a promising candidate for pain relief. Further research is needed to fully understand the role of PIANP in pain signaling and its potential as a drug target.

Protein Name: PILR Alpha Associated Neural Protein

Functions: Acts as a ligand for PILRA in neural tissues, where it may be involved in immune regulation

More Common Targets

PIAS1 | PIAS2 | PIAS3 | PIAS4 | PIBF1 | PICALM | PICART1 | PICK1 | PICSAR | PID1 | PIDD1 | PIERCE1 | PIERCE2 | PIEZO1 | PIEZO2 | PIF1 | PIFO | PIGA | PIGB | PIGBOS1 | PIGC | PIGF | PIGG | PIGH | PIGK | PIGL | PIGM | PIGN | PIGO | PIGP | PIGQ | PIGR | PIGS | PIGT | PIGU | PIGV | PIGW | PIGX | PIGY | PIGZ | PIH1D1 | PIH1D2 | PIK3AP1 | PIK3C2A | PIK3C2B | PIK3C2G | PIK3C3 | PIK3CA | PIK3CA-DT | PIK3CB | PIK3CD | PIK3CD-AS1 | PIK3CD-AS2 | PIK3CG | PIK3IP1 | PIK3IP1-DT | PIK3R1 | PIK3R2 | PIK3R3 | PIK3R4 | PIK3R5 | PIK3R6 | PIKFYVE | PILRA | PILRB | Pim Kinase | PIM1 | PIM2 | PIM3 | PIMREG | PIN1 | PIN1-DT | PIN1P1 | PIN4 | PINCR | PINK1 | PINK1-AS | PINLYP | PINX1 | PIP | PIP4K2A | PIP4K2B | PIP4K2C | PIP4P1 | PIP4P2 | PIP5K1A | PIP5K1B | PIP5K1C | PIP5K1P1 | PIP5KL1 | PIPOX | PIPSL | PIR | PIR-FIGF | PIRAT1 | PIRT | PISD | PISRT1 | PITHD1 | PITPNA