PIP5KL1: A Potential Drug Target and Biomarker for Phosphatidylinositol 4-Phosphate 5-Kinase-Like Protein 1

Target Name: PIP5KL1

NCBI ID: G138429

PIP5KL1: A Potential Drug Target and Biomarker for Phosphatidylinositol 4-Phosphate 5-Kinase-Like Protein 1

Introduction

Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 (PIP5KL1) is a protein that plays a crucial role in cellular signaling. It is a key enzyme in the PI3K/Akt signaling pathway, which is involved in various cellular processes, including cell survival , growth, and angiogenesis. The PI3K/Akt signaling pathway is a promising target for the development of new drugs for various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.

PIP5KL1 is a 21-kDa protein that is expressed in various tissues and cells. It is highly conserved, with a calculated pI of 6.5 and a predicted localization in the cytoplasm. PIP5KL1 is a critical enzyme for the PI3K/Akt signaling pathway. It catalyzes the conversion of inositol 1,4,6-trisphosphate (IP3) to IP4 and phosphatidylinositol 4-phosphate (PIP2), which are the key intermediate steps in the PI3K/Akt signaling pathway.

The PI3K/Akt signaling pathway is a complex and highly regulated signaling pathway that is involved in various cellular processes, including cell survival, growth, and angiogenesis. It is a promising target for the development of new drugs for various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.

PIP5KL1 is a key enzyme in the PI3K/Akt signaling pathway. It catalyzes the conversion of inositol 1,4,6-trisphosphate (IP3) to IP4 and phosphatidylinositol 4-phosphate (PIP2), which are the key intermediate steps in the PI3K/ Akt signaling pathway. The PI3K/Akt signaling pathway is a highly regulated signaling pathway that is involved in various cellular processes, including cell survival, growth, and angiogenesis.

PIP5KL1 is a potential drug target because of its role in the PI3K/Akt signaling pathway. The PI3K/Akt signaling pathway is a highly regulated signaling pathway that is involved in various cellular processes, including cell survival, growth, and angiogenesis. Therefore, inhibiting the PI3K/Akt signaling pathway may be a promising strategy for the development of new drugs for various diseases.

PIP5KL1 is also a potential biomarker for the PI3K/Akt signaling pathway. The PI3K/Akt signaling pathway is a highly regulated signaling pathway that is involved in various cellular processes, including cell survival, growth, and angiogenesis. Therefore, measuring the levels of PIP5KL1 may be a useful biomarker for the PI3K/Akt signaling pathway.

Conclusion

PIP5KL1 is a protein that plays a crucial role in the PI3K/Akt signaling pathway. It is highly conserved and predicted to localize in the cytoplasm. PIP5KL1 is a potential drug target and biomarker for the PI3K/Akt signaling pathway. inhibiting the PI3K/Akt signaling pathway may be a promising strategy for the development of new drugs for various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Additionally, measuring the levels of PIP5KL1 may be a useful biomarker for the PI3K/Akt signaling pathway.

Protein Name: Phosphatidylinositol-4-phosphate 5-kinase Like 1

Functions: May act as a scaffold to localize and regulate type I PI(4)P 5-kinases to specific compartments within the cell, where they generate PI(4,5)P2 for actin nucleation, signaling and scaffold protein recruitment and conversion to PI(3,4,5)P3

More Common Targets