Target Name: PKDREJ
NCBI ID: G10343
Other Name(s): polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin) | PKDRE_HUMAN | polycystic kidney disease and receptor for egg jelly-related protein | PKD and REJ homolog | Polycystin family receptor for egg jelly | Polycystic kidney disease and receptor for egg jelly-related protein | polycystin family receptor for egg jelly | polycystin (PKD) family receptor for egg jelly

PKDREJ: A Potential Drug Target for PKD

Polycystic Kidney Disease (PKD) is a genetic disorder that affects the kidneys and can cause a range of symptoms and complications. PKD is a diverse disease that can be divided into two main types, PKD1 and PKD2. PKD1 is the most common form of PKD and is caused by a deficiency in the gene PKDREJ, while PKD2 is caused by a mutation in the geneRej. PKDREJ and Rej are homologs, which means they share a common ancestor gene. In this article, we will discuss PKDREJ and its potential as a drug target or biomarker for the treatment of PKD.

PKDREJ is a gene that encodes a protein known as polycystic kidney disease receptor (PKDR). PKDR is a transmembrane protein that is involved in the regulation of cell signaling pathways. It is a G protein-coupled receptor (GPCR), which means it uses a protein called GPCR signaling to communicate with other cells. PKDR has been shown to play a role in the development and progression of PKD.

One of the functions of PKDR is to regulate the production of new blood vessels in the kidneys. PKDR has been shown to be involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed in the body. Angiogenesis is a critical process for the development and maintenance of normal tissues and organs, including the kidneys.

In PKD, the absence of PKDR can lead to the formation of excess blood vessels in the kidneys, which can causePKDREJ and its potential as a drug target or biomarker for the treatment of PKD.

Another function of PKDR is that it is involved in the regulation of cell signaling pathways that are important for the development and maintenance of normal tissues and organs. PKDR has been shown to be involved in the regulation of cell proliferation, cell survival, and cell differentiation.

PKDR has also been shown to be involved in the regulation of cellular signaling pathways that are important for the development and maintenance of normal tissues and organs. PKDR has been shown to be involved in the regulation of cell proliferation, cell survival, and cell differentiation.

In addition to its role in cell signaling pathways, PKDR has also been shown to be involved in the regulation of inflammation. PKDR has been shown to be involved in the regulation of inflammation and has been shown to play a role in the development of chronic kidney diseases (CKD).

PKDR has also been shown to be involved in the regulation of the immune response. PKDR has been shown to be involved in the regulation of the immune response and has been shown to play a role in the development of autoimmune diseases, including PKD.

In conclusion, PKDREJ is a gene that encodes a protein involved in the regulation of cell signaling pathways, angiogenesis, inflammation, and immune response. PKDREJ has been shown to play a role in the development and progression of PKD. As a result, PKDREJ may be a potential drug target or biomarker for the treatment of PKD. Further research is needed to fully understand the role of PKDREJ in PKD and to develop effective treatments for this disease.

Protein Name: Polycystin Family Receptor For Egg Jelly

Functions: May have a central role in fertilization. May generate a Ca(2+) transporting channel directly involved in initiating the acrosome reaction of the sperm

More Common Targets

PKHD1 | PKHD1L1 | PKIA | PKIA-AS1 | PKIB | PKIG | PKLR | PKM | PKMP1 | PKMYT1 | PKN1 | PKN2 | PKN2-AS1 | PKN3 | PKNOX1 | PKNOX2 | PKNOX2-DT | PKP1 | PKP2 | PKP3 | PKP4 | PKP4-AS1 | PLA1A | PLA2G10 | PLA2G12A | PLA2G12AP1 | PLA2G12B | PLA2G15 | PLA2G1B | PLA2G2A | PLA2G2C | PLA2G2D | PLA2G2E | PLA2G2F | PLA2G3 | PLA2G4A | PLA2G4B | PLA2G4C | PLA2G4D | PLA2G4E | PLA2G4F | PLA2G5 | PLA2G6 | PLA2G7 | PLA2R1 | PLAA | PLAAT1 | PLAAT2 | PLAAT3 | PLAAT4 | PLAAT5 | PLAC1 | PLAC4 | PLAC8 | PLAC8L1 | PLAC9 | PLAC9P1 | PLAG1 | PLAGL1 | PLAGL2 | Plasma Membrane Calcium ATPase | PLAT | Platelet Glycoprotein Ib Complex | Platelet-activating factor acetylhydrolase isoform 1B complex | Platelet-Derived Growth Factor (PDGF) | Platelet-Derived Growth Factor Receptor | PLAU | PLAUR | PLB1 | PLBD1 | PLBD1-AS1 | PLBD2 | PLCB1 | PLCB2 | PLCB3 | PLCB4 | PLCD1 | PLCD3 | PLCD4 | PLCE1 | PLCE1-AS2 | PLCG1 | PLCG1-AS1 | PLCG2 | PLCH1 | PLCH2 | PLCL1 | PLCL2 | PLCXD1 | PLCXD2 | PLCXD3 | PLCZ1 | PLD1 | PLD2 | PLD3 | PLD4 | PLD5 | PLD6 | PLEC | PLEK