Target Name: PLD2
NCBI ID: G5338
Other Name(s): Choline phosphatase 2 | phospholipase D2 | Phospholipase D2, transcript variant 1 | Phospholipase D2 | PLD 2 | Phosphatidylcholine-hydrolyzing phospholipase D2 | hPLD2 | choline phosphatase 2 | Phospholipase D2 (isoform PLD2A) | PLD1C | PLD2_HUMAN | phosphatidylcholine-hydrolyzing phospholipase D2 | PLD2 variant 1

PLD2: A Potential Drug Target and Biomarker

Platelet-derived neurotrophic factor (PDGF) is a protein that plays a crucial role in the development and maintenance of neural tissue, including brain. PDGF is generated from platelets, which are the blood cells that are responsible for clotting and healing injuries. In recent years, the discovery of PDGF has led to a growing interest in its potential therapeutic applications, particularly in the field of neurodegenerative diseases.

One of the most promising applications of PDGF is its potential as a drug target. The ability of PDGF to stimulate the growth and survival of neural cells makes it an attractive target for drug development. By targeting PDGF signaling, researchers hope to develop new treatments for conditions such as Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders.

In addition to its potential as a drug target, PDGF has also been identified as a potential biomarker for several neurodegenerative diseases. The ability of PDGF to stimulate the growth and survival of neural cells makes it an attractive target for the development of diagnostic tools for these conditions. For example, researchers have used PDGF to label neurons in the brain and track their movement in order to understand the effects of neurotransmitters on neural activity.

PDGF has also been shown to play a role in several other biological processes, including cell signaling, angiogenesis, and tissue repair. These properties make PDGF an attractive target for the development of new therapies for a variety of conditions.

The potential applications of PDGF are vast and continue to be explored by researchers. As research continues, it is likely that new uses for PDGF will be discovered, and existing applications will become even more effective. For example, PDGF has been shown to be effective in treating conditions such as skin cancer and birth defects, and further research is being conducted to see if it has potential as a cancer and regenerative therapy.

In conclusion, PDGF is a protein that has the potential to revolutionize the field of neurodegenerative diseases. As a drug target and biomarker, PDGF is an attractive target for drug development, and its potential applications continue to grow. Further research is being conducted to fully understand the role of PDGF in neural development and to explore its potential as a therapeutic tool.

Protein Name: Phospholipase D2

Functions: Function as phospholipase selective for phosphatidylcholine (PubMed:9582313). May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity)

More Common Targets

PLD3 | PLD4 | PLD5 | PLD6 | PLEC | PLEK | PLEK2 | PLEKHA1 | PLEKHA2 | PLEKHA3 | PLEKHA4 | PLEKHA5 | PLEKHA6 | PLEKHA7 | PLEKHA8 | PLEKHA8P1 | PLEKHB1 | PLEKHB2 | PLEKHD1 | PLEKHF1 | PLEKHF2 | PLEKHG1 | PLEKHG2 | PLEKHG3 | PLEKHG4 | PLEKHG4B | PLEKHG5 | PLEKHG6 | PLEKHG7 | PLEKHH1 | PLEKHH2 | PLEKHH3 | PLEKHJ1 | PLEKHM1 | PLEKHM1P1 | PLEKHM2 | PLEKHM3 | PLEKHN1 | PLEKHO1 | PLEKHO2 | PLEKHS1 | PLET1 | Plexin | PLG | PLGLA | PLGLB1 | PLGLB2 | PLGRKT | PLIN1 | PLIN2 | PLIN3 | PLIN4 | PLIN5 | PLK1 | PLK2 | PLK3 | PLK4 | PLK5 | PLLP | PLN | PLOD1 | PLOD2 | PLOD3 | PLP1 | PLP2 | PLPBP | PLPP1 | PLPP2 | PLPP3 | PLPP4 | PLPP5 | PLPP6 | PLPP7 | PLPPR1 | PLPPR2 | PLPPR3 | PLPPR4 | PLPPR5 | PLPPR5-AS1 | PLRG1 | PLS1 | PLS3 | PLSCR1 | PLSCR2 | PLSCR3 | PLSCR4 | PLSCR5 | PLTP | PLUT | PLVAP | PLXDC1 | PLXDC2 | PLXNA1 | PLXNA2 | PLXNA3 | PLXNA4 | PLXNB1 | PLXNB2 | PLXNB3 | PLXNC1