Plekha-1: A Protein Implicated in Autoimmune and Cell Death (G59338)

Target Name: PLEKHA1

NCBI ID: G59338

Other Name(s): TAPP1 | Pleckstrin homology domain-containing family A member 1 | pleckstrin homology domain containing A1 | TAPP-1 | Pleckstrin homology domain containing A1, transcript variant 2 | PH domain-containing family A member 1 | PKHA1_HUMAN | tandem PH domain-containing protein 1 | Tandem PH domain containing protein-1 | Pleckstrin homology domain-containing family A member 1 (isoform 1) | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | Tandem PH domain-containing protein 1 | PLEKHA1 variant 2 | Pleckstrin homology domain-containing protein family A member 1

Plekha-1: A Protein Implicated in Autoimmune and Cell Death

PLEKHA1 (TAPP1) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the T-cell antigen 6 (TCA6) family, which includes proteins that are involved in the immune response.

One of the functions of PLEKHA1 is to regulate the development and function of immune cells. It is known to play a role in the development of autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis.

Additionally, PLEKHA1 has also been shown to be involved in the regulation of cell death, which is a critical process that helps maintain the integrity of tissues.

Plekha-1 is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the T-cell antigen 6 (TCA6) family, which includes proteins that are involved in the immune response and cell death.

One of the functions of PLEKHA1 is to regulate the development and function of immune cells. It is known to play a role in the development of autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis.

Additionally, PLEKHA1 has also been shown to be involved in the regulation of cell death, which is a critical process that helps maintain the integrity of tissues.

Plekha-1 has also been shown to play a role in the regulation of the immune response. It is known to be involved in the development of T-cells, which are a critical part of the immune system. T-cells are responsible for recognizing and responding to foreign substances in the body, and PLEKHA1 is thought to be involved in this process.

In addition to its role in the immune response, PLEKHA1 has also been shown to be involved in the regulation of cell signaling pathways. It is known to play a role in the regulation of the PI3K/Akt signaling pathway, which is a critical pathway that is involved in the regulation of cell growth and survival.

Plekha-1 is also known to be involved in the regulation of the mitochondrial network. Mitochondria are organelles that are responsible for generating energy for the cell, and they are thought to be involved in the regulation of a wide range of cellular processes, including cell death. PLEKHA1 is thought to be involved in the regulation of mitochondrial network, which is responsible for the regulation of cell death.

In conclusion, PLEKHA1 is a protein that is involved in a wide range of cellular processes in the body. It is known to play a role in the regulation of the immune response, cell signaling pathways, and mitochondrial network. Because of its involvement in these processes, PLEKHA1 is thought to be a potential drug target or biomarker for a wide range of diseases.

Protein Name: Pleckstrin Homology Domain Containing A1

Functions: Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane

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