PLPP7: Key Enzyme in Phospholipid Biosynthesis and Cell Signaling
PLPP7: Key Enzyme in Phospholipid Biosynthesis and Cell Signaling
PLPP7, also known as phospholipid phosphatase 7 (inactive), is a protein that is expressed in various cell types throughout the body. It is a key enzyme in the phospholipid biosynthesis pathway, which is responsible for the production of the major types of phospholipids, including phosphatidylcholine (PC) and phosphatidylserine (PS). PC is a major component of cell membranes, while PS is mainly found in the cytosol of cells.
The PLPP7 enzyme is highly conserved across various species, which suggests that it has an important function in the cell. Studies have shown that PLPP7 is involved in various cellular processes, including cell signaling, protein synthesis, and membrane structure. It is also involved in the regulation of cellular processes that are critical for the survival of the cell, such as cell division, apoptosis, and inflammation.
One of the key functions of PLPP7 is its role in the regulation of cell signaling. PLPP7 is involved in the production of various signaling molecules, including phosphatidyl choline (PC), which is a key component of the cell membrane. The production of PC is regulated by various signaling pathways, including the TOR signaling pathway, which is involved in cell growth, metabolism, and survival.
In addition to its role in cell signaling, PLPP7 is also involved in the regulation of protein synthesis. PLPP7 is a key enzyme in the synthesis of the protein Myosin, which is involved in muscle contractions and other cellular processes. The activity of PLPP7 is regulated by various factors, including the levels of ATP and other nutrients in the cell.
PLPP7 is also involved in the regulation of cellular processes that are critical for the survival of the cell, such as cell division and apoptosis. PLPP7 is involved in the production of the protein p16INK4a, which is involved in the regulation of cell apoptosis. In addition , PLPP7 is involved in the production of the protein Bcl-2, which is involved in the regulation of cell growth and apoptosis.
In conclusion, PLPP7 is a protein that is involved in various cellular processes that are critical for the survival of the cell. Its role in the regulation of cell signaling, protein synthesis, and cellular processes such as cell division and apoptosis makes it an attractive drug target or biomarker. Further research is needed to fully understand the functions of PLPP7 and its potential as a drug.
Protein Name: Phospholipid Phosphatase 7 (inactive)
Functions: Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity (By similarity)
More Common Targets
PLPPR1 | PLPPR2 | PLPPR3 | PLPPR4 | PLPPR5 | PLPPR5-AS1 | PLRG1 | PLS1 | PLS3 | PLSCR1 | PLSCR2 | PLSCR3 | PLSCR4 | PLSCR5 | PLTP | PLUT | PLVAP | PLXDC1 | PLXDC2 | PLXNA1 | PLXNA2 | PLXNA3 | PLXNA4 | PLXNB1 | PLXNB2 | PLXNB3 | PLXNC1 | PLXND1 | PM20D1 | PM20D2 | PMAIP1 | PMCH | PMCHL1 | PMCHL2 | PMEL | PMEPA1 | PMF1 | PMF1-BGLAP | PMFBP1 | PML | PMM1 | PMM2 | PMP2 | PMP22 | PMPCA | PMPCB | PMS1 | PMS2 | PMS2P1 | PMS2P12 | PMS2P13 | PMS2P2 | PMS2P3 | PMS2P4 | PMS2P5 | PMS2P9 | PMVK | PNCK | PNISR | PNISR-AS1 | PNKD | PNKP | PNKY | PNLDC1 | PNLIP | PNLIPRP1 | PNLIPRP2 | PNLIPRP3 | PNMA1 | PNMA2 | PNMA3 | PNMA5 | PNMA6A | PNMA8A | PNMA8B | PNMT | PNN | PNO1 | PNOC | PNP | PNPLA1 | PNPLA2 | PNPLA3 | PNPLA4 | PNPLA5 | PNPLA6 | PNPLA7 | PNPLA8 | PNPO | PNPT1 | PNRC1 | PNRC2 | POC1A | POC1B | POC1B-GALNT4 | POC5 | PODN | PODNL1 | PODXL | PODXL2