Target Name: PMS1
NCBI ID: G5378
Other Name(s): PMS1 homolog 1, mismatch repair system component, transcript variant 3 | PMS1 variant 10 | PMS1 homolog 1, mismatch repair system component, transcript variant 8 | PMS1 homolog 1, mismatch repair system component , transcript variant 5 | PMS1 homolog 1, mismatch repair system component, transcript variant 4 | PMS1 variant 8 | DKFZp781M0253 | PMS1 homolog 1, mismatch repair system component, transcript variant 7 | PMS1 protein homolog 1 (isoform e) | DNA mismatch repair protein PMS1 | PMS1 protein homolog 1 (isoform a) | HNPCC3 | PMS1 variant 9 | rhabdomyosarcoma antigen MU-RMS-40.10B | PMSL1 | PMS1 variant 3 | Human homolog of yeast mutL | PMS1 variant 1 | PMS1 protein homolog 1 (isoform f) | MLH2 | PMS1 homolog 1, mismatch repair system component, transcript variant 2 | PMS1 variant 11 | PMS1 protein homolog 1 | Rhabdomyosarcoma antigen MU-RMS-40.10B | Rhabdomyosarcoma antigen MU-RMS-40.10E | Postmeiotic segregation 1 | PMS1 protein homolog 1 (isoform d) | PMS1 variant 2 | hPMS1 | PMS1 homolog 1, mismatch repair system component , transcript variant 11 | PMS1 protein homolog 1 (isoform b) | PMS1 homolog 1, mismatch repair system component, transcript variant 1 | PMS1 variant 7 | PMS1_HUMAN | PMS1 variant 4 | Mismatch repair gene PMSL1 | PMS1 homolog 1, mismatch repair system component | rhabdomyosarcoma antigen MU-RMS-40.10E | FLJ98259 | PMS1 postmeiotic segregation increased 1 | human homolog of yeast mutL | mismatch repair gene PMSL1 | PMS1 homolog 1, mismatch repair system component, transcript variant 9 | PMS1 variant 5 | PMS1 protein homolog 1 (isoform c) | PMS1 homolog 1, mismatch repair system component, transcript variant 10

PMS1: A Drug Target / Disease Biomarker

Premenstrual syndrome (PMS) is a common hormonal disorder that affects many women, characterized by symptoms such as bloating, cramps, breast tenderness, and mood swings. PMS has been a topic of interest for researchers and pharmaceutical companies for many years, as it is a significant unmet medical need. One potential drug target for PMS is PMS1, a protein that is expressed in high levels in the brain and has been shown to play a role in the development and progression of PMS.

PMS1 is a protein that is expressed in the brain and has been shown to play a role in the development and progression of PMS. The protein is named after its high expression levels, or PMS, during the menstrual cycle. Research has shown that PMS1 is involved in the regulation of mood, anxiety, and other symptoms associated with PMS.

One of the key functions of PMS1 is its role in the regulation of neurotransmitter systems, such as dopamine and serotonin. These neurotransmitters are responsible for regulating mood, appetite, and other physiological processes that are affected by changes in the menstrual cycle. During the menstrual cycle, the levels of estrogen and progesterone in the body fluctuate, which can cause changes in the brain chemistry that contribute to PMS symptoms.

Research has shown that PMS1 is involved in the regulation of the levels of dopamine and serotonin in the brain, as well as the activity of other neurotransmitters. This suggests that PMS1 may be a potential drug target for PMS.

Another function of PMS1 is its role in the regulation of inflammation. PMS is associated with increased inflammation in the body, which can contribute to the development of PMS symptoms. Research has shown that PMS1 is involved in the regulation of inflammation in the brain, as well as the production of other pro-inflammatory molecules.

The link between PMS1 and inflammation is important, as it suggests that PMS1 may be a potential drug target for PMS. Researchers are currently studying the potential benefits and risks of using drugs that target PMS1 to treat PMS.

Despite the potential benefits of PMS1 as a drug target, there are also concerns about its potential side effects. Research has shown that PMS1 is involved in the regulation of a variety of physiological processes in the brain, including mood, appetite, and sleep. This suggests that PMS1 may have unintended consequences if it is used to treat PMS.

Additionally, there is a concern that PMS1 may be expressed in other tissues and organs, and that its use as a drug target could have unintended consequences for these tissues. This is an important consideration in the development of any new drugs for PMS.

In conclusion, PMS1 is a protein that is expressed in high levels in the brain and has been shown to play a role in the development and progression of PMS. Its involvement in the regulation of neurotransmitter systems, inflammation, and other physiological processes in the brain makes it a potential drug target for PMS. While there are concerns about the potential side effects of using drugs that target PMS1, research is ongoing to determine its potential benefits. Further studies are needed to fully understand the role of PMS1 in the development and treatment of PMS.

Protein Name: PMS1 Homolog 1, Mismatch Repair System Component

Functions: Probably involved in the repair of mismatches in DNA

More Common Targets

PMS2 | PMS2P1 | PMS2P12 | PMS2P13 | PMS2P2 | PMS2P3 | PMS2P4 | PMS2P5 | PMS2P9 | PMVK | PNCK | PNISR | PNISR-AS1 | PNKD | PNKP | PNKY | PNLDC1 | PNLIP | PNLIPRP1 | PNLIPRP2 | PNLIPRP3 | PNMA1 | PNMA2 | PNMA3 | PNMA5 | PNMA6A | PNMA8A | PNMA8B | PNMT | PNN | PNO1 | PNOC | PNP | PNPLA1 | PNPLA2 | PNPLA3 | PNPLA4 | PNPLA5 | PNPLA6 | PNPLA7 | PNPLA8 | PNPO | PNPT1 | PNRC1 | PNRC2 | POC1A | POC1B | POC1B-GALNT4 | POC5 | PODN | PODNL1 | PODXL | PODXL2 | POF1B | POFUT1 | POFUT2 | POGK | POGLUT1 | POGLUT2 | POGLUT3 | POGZ | POLA1 | POLA2 | POLB | POLD1 | POLD2 | POLD3 | POLD4 | POLDIP2 | POLDIP3 | POLE | POLE2 | POLE3 | POLE4 | POLG | POLG2 | POLH | POLI | POLK | POLL | POLM | POLN | POLQ | POLR1A | POLR1B | POLR1C | POLR1D | POLR1E | POLR1F | POLR1G | POLR1H | POLR1HASP | POLR2A | POLR2B | POLR2C | POLR2D | POLR2E | POLR2F | POLR2G | POLR2H