POLR1G: Potential Drug Target for Neurological Disorders (G10849)

Target Name: POLR1G

NCBI ID: G10849

POLR1G: Potential Drug Target for Neurological Disorders

POLR1G (PRT1G) is a protein that is expressed in the brain and is known for its role in the regulation of microRNA (miRNA) levels. It has been shown to play a crucial role in the development and progression of several neurological disorders, including Alzheimer's disease and Parkinson's disease.

Recent studies have also suggested that POLR1G may have potential as a drug target or biomarker for certain neurological disorders. For example, some researchers have found that targeting the expression of POLR1G has been shown to improve cognitive function in individuals with Alzheimer's disease.

Additionally, other studies have shown that targeting the miRNA levels of POLR1G has been shown to be effective in reducing the amount of neurodegeneration in individuals with Parkinson's disease.

The potential drug targets for POLR1G are still being explored, but it is clear that it is an important protein that is involved in the development and progression of several neurological disorders. Further research is needed to fully understand its role and potential as a drug target or biomarker.

Protein Name: RNA Polymerase I Subunit G

Functions: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation

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