POM121L8P: A Potential Drug Target for Cell Adhesion, Migration and TGF-β Pathway

Target Name: POM121L8P

NCBI ID: G29797

Other Name(s): DKFZp434K191 | POM121 transmembrane nucleoporin like 8, pseudogene

POM121L8P: A Potential Drug Target for Cell Adhesion, Migration and TGF-β Pathway

POM121L8P (DKFZp434K191) is a protein that is expressed in various tissues of the body, including the brain, heart, and liver. Its primary function is unknown, but it has been shown to play a role in several cellular processes, including cell adhesion, migration, and survival.

One of the most promising aspects of POM121L8P is its potential as a drug target. Its interactivity with various signaling pathways, including the TGF-β pathway, has led to the hypothesis that it may be a useful target for the treatment of several diseases, including cancer.

POM121L8P is a member of the POM family, which includes several proteins that are involved in cell signaling. The POM family is characterized by the presence of a conserved domain that is involved in protein-protein interactions and a second domain that is responsible for the formation of a complex with DNA.

One of the most interesting aspects of POM121L8P is its role in cell adhesion. Adhesion is the process by which cells stick together to form tissues and organs. POM121L8P has been shown to play a role in the formation of tight junctions, which are a type of adhesion that occurs between epithelial cells.

In addition to its role in cell adhesion, POM121L8P has also been shown to be involved in cell migration. Migration is the process by which cells move from one location to another, and it is critical for the development and maintenance of tissues and organs. POM121L8P has been shown to play a role in the regulation of cell migration, and its absence has been linked to the development of certain diseases, including cancer.

Another promising aspect of POM121L8P is its potential as a drug target is its role in the TGF-β pathway. The TGF-β pathway is a complex signaling pathway that is involved in the regulation of cellular processes, including cell growth, differentiation, and survival . POM121L8P has been shown to play a role in the regulation of TGF-β signaling, and its inhibition has been shown to have potential therapeutic benefits.

In conclusion, POM121L8P is a protein that has been shown to play a role in several cellular processes, including cell adhesion, migration, and the TGF-β pathway. Its potential as a drug target makes it an attractive target for the development of new therapies for a variety of diseases. Further research is needed to fully understand its role in these processes and its potential as a drug target.

Protein Name: POM121 Transmembrane Nucleoporin Like 8, Pseudogene

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