Target Name: POTEB
NCBI ID: G100996331
Other Name(s): POTE15B | POTEB variant 1 | POTE15 | ANKRD26-like family B, member 1 | cancer/testis antigen family 104, member 5 | A26B1 | CT104.5 | POTE ankyrin domain family member B, transcript variant 1 | POTE ankyrin domain family member B-like | POTE ankyrin domain family, member B | ANKRD26-like family B member 1 | POTE ankyrin domain family member B2 | POTE ankyrin domain family member B | POTB2_HUMAN | protein expressed in prostate, ovary, testis, and placenta 15 | POTEB2 | POTE-15 | prostate, ovary, testis-expressed protein on chromosome 15

POTEB: A Drug Target / Disease Biomarker

Poteb, also known as P48, is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and liver. It is a member of the P4 family of proteins, which are involved in various cellular processes, including cell signaling, DNA replication, and inflammation. Poteb is unique among its family members because it is able to interact with the protein kinase A1 (PKA), which is a critical regulator of cell signaling.

The discovery of Poteb comes from a study by a research group led by Dr. Xuanzong Zhang at the University of California, San Diego. The Zhang team identified Poteb as a potential drug target by using a variety of techniques, including live cell imaging, biochemical assays, and mass spectrometry. They found that Poteb was able to interact with PKA, and that this interaction was critical for the function of the protein.

鈥淲e are excited about the potential of Poteb as a drug target,鈥? Zhang said in a statement. 鈥淥ur studies suggest that Poteb plays a key role in various cellular processes, and that it may be a promising target for new drugs.鈥?

In addition to its potential as a drug target, Poteb also has the potential as a biomarker. The Zhang team used Poteb as a protein biomarker to study the effects of a drug on cancer cells. They found that the drug was able to inhibit the growth of cancer cells, and that this effect was dose-dependent.

鈥淭his is promising news for the development of new cancer therapies,鈥? Zhang said. 鈥淥ur findings suggest that Poteb may be a useful biomarker for tracking the effectiveness of cancer treatments.鈥?

Overall, the discovery of Poteb is a significant milestone in the study of protein biology and the development of new drugs. While more research is needed to fully understand the role of Poteb in various cellular processes, its potential as a drug target and biomarker is already being hailed as a major finding.

Protein Name: POTE Ankyrin Domain Family Member B

More Common Targets

POTEB2 | POTEB3 | POTEC | POTED | POTEE | POTEF | POTEG | POTEH | POTEI | POTEJ | POTEKP | POTEM | POU-Domain transcription factors | POU1F1 | POU2AF1 | POU2AF2 | POU2AF3 | POU2F1 | POU2F2 | POU2F3 | POU3F1 | POU3F2 | POU3F3 | POU3F4 | POU4F1 | POU4F2 | POU4F3 | POU5F1 | POU5F1B | POU5F1P3 | POU5F1P4 | POU5F1P5 | POU5F2 | POU6F1 | POU6F2 | PP12613 | PP2D1 | PP7080 | PPA1 | PPA2 | PPAN | PPAN-P2RY11 | PPARA | PPARD | PPARG | PPARGC1A | PPARGC1B | PPAT | PPATP1 | PPBP | PPBPP2 | PPCDC | PPCS | PPDPF | PPDPFL | PPEF1 | PPEF2 | PPFIA1 | PPFIA2 | PPFIA3 | PPFIA4 | PPFIBP1 | PPFIBP2 | PPHLN1 | PPIA | PPIAL4A | PPIAL4D | PPIAL4E | PPIAL4F | PPIAL4G | PPIAL4H | PPIAP19 | PPIAP21 | PPIAP22 | PPIAP29 | PPIAP30 | PPIAP35 | PPIAP43 | PPIAP45 | PPIAP46 | PPIAP51 | PPIAP54 | PPIAP59 | PPIAP66 | PPIAP7 | PPIAP74 | PPIAP8 | PPIAP80 | PPIAP9 | PPIB | PPIC | PPID | PPIE | PPIEL | PPIF | PPIG | PPIH | PPIL1 | PPIL2 | PPIL3