PNN: A Drug Target / Disease Biomarker (G5411)

Target Name: PNN

NCBI ID: G5411

PNN: A Drug Target / Disease Biomarker

PNN, short for protein-protein interaction, is a biological phenomenon that has been identified as a potential drug target and biomarker. It refers to the interaction between two proteins, which can be regulated by various factors such as mutations, mutations, and interactions with other molecules.

PNP has been identified as a potential drug target due to its involvement in various physiological processes in the body. For instance, PNP has been shown to play a role in the regulation of cell growth, differentiation, and survival. It has also been linked to various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

One of the key challenges in studying PNP is its complex nature. PNP interactions are often dynamic and can be influenced by various factors such as the local environment and the presence of other molecules. Understanding the dynamics of PNP interactions is crucial for developing effective drugs and for identifying potential biomarkers.

In addition to its potential as a drug target, PNP has also been identified as a potential biomarker for various diseases. For instance, studies have shown that changes in PNP levels can be associated with certain diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

The discovery of PNP as a potential drug target and biomarker has significant implications for the development of new treatments for various diseases. By targeting PNP interactions, researchers can develop drugs that can inhibit the activity of PNP and reduce the risk of disease.

Furthermore, the study of PNP has also led to a greater understanding of its underlying mechanisms. The dynamic nature of PNP interactions has led to the development of new models for understanding how PNP interactions are regulated. These models have provided new insights into the regulation of PNP interactions and have led to the development of new therapeutic strategies.

In conclusion, PNP is a protein-protein interaction that has significant implications for the development of new treatments for various diseases. Its complex nature and the involvement in various physiological processes make it an attractive target for drug development. Further research is needed to fully understand the regulation of PNP interactions and to develop effective treatments for PNP-related diseases.

Protein Name: Pinin, Desmosome Associated Protein

Functions: Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation of alternative pre-mRNA splicing. Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites. Component of the PSAP complex which binds RNA in a sequence-independent manner and is proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. Involved in the establishment and maintenance of epithelia cell-cell adhesion. Potential tumor suppressor for renal cell carcinoma

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