Target Name: PLEKHG1
NCBI ID: G57480
Other Name(s): ARHGEF41 | OTTHUMP00000017413 | FLJ31738 | PKHG1_HUMAN | pleckstrin homology and RhoGEF domain containing G1 | KIAA1209 | Pleckstrin homology and RhoGEF domain containing G1, transcript variant 3 | Pleckstrin homology domain-containing family G member 1 (isoform c) | Pleckstrin homology domain-containing family G member 1 | PLEKHG1 variant 3 | OTTHUMP00000017414 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1

Plekhoggin: A Protein Involved in Cellular Signaling Pathways

PLEKHG1 (ARHGEF41) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the tyrosine kinase receptor (TKR) family and is involved in the regulation of cellular signaling pathways.

Plekhoggin is a protein that is known to interact with the protein Fyn, which is a key signaling molecule in the TKR family. This interaction between PLEKHG1 and Fyn has been implicated in the regulation of cellular signaling pathways, including the regulation of cell growth, , and survival.

One of the functions of PLEKHG1 is to regulate the activity of the protein kinase AAF/PSC, which is a key enzyme involved in the regulation of cellular signaling pathways. PLEKHG1 has been shown to interact with AAF/PSC and to regulate its activity. This The interaction between PLEKHG1 and AAF/PSC is thought to play a role in the regulation of cellular signaling pathways, including the regulation of cell growth, differentiation, and survival.

Another function of PLEKHG1 is to regulate the activity of the protein tyrosine kinase (TK), which is involved in the regulation of cellular signaling pathways. PLEKHG1 has been shown to interact with TK and to regulate its activity. This interaction between PLEKHG1 and TK is thought to play a role in the regulation of cellular signaling pathways, including the regulation of cell growth, differentiation, and survival.

Plekhoggin has also been shown to interact with the protein p53, which is a key regulator of cellular signaling pathways. PLEKHG1 has been shown to regulate the activity of p53 and to play a role in the regulation of cellular signaling pathways. This interaction between PLEKHG1 and p53 is thought to play a role in the regulation of cellular signaling pathways, including the regulation of cell growth, differentiation, and survival.

In conclusion, PLEKHG1 (ARHGEF41) is a protein that is involved in the regulation of cellular signaling pathways. Its interaction with the protein Fyn, AAF/PSC, TK, and p53 suggests that it plays a role in the regulation of cell growth, differentiation , and survival. Therefore, PLEKHG1 may be a drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

Protein Name: Pleckstrin Homology And RhoGEF Domain Containing G1

More Common Targets

PLEKHG2 | PLEKHG3 | PLEKHG4 | PLEKHG4B | PLEKHG5 | PLEKHG6 | PLEKHG7 | PLEKHH1 | PLEKHH2 | PLEKHH3 | PLEKHJ1 | PLEKHM1 | PLEKHM1P1 | PLEKHM2 | PLEKHM3 | PLEKHN1 | PLEKHO1 | PLEKHO2 | PLEKHS1 | PLET1 | Plexin | PLG | PLGLA | PLGLB1 | PLGLB2 | PLGRKT | PLIN1 | PLIN2 | PLIN3 | PLIN4 | PLIN5 | PLK1 | PLK2 | PLK3 | PLK4 | PLK5 | PLLP | PLN | PLOD1 | PLOD2 | PLOD3 | PLP1 | PLP2 | PLPBP | PLPP1 | PLPP2 | PLPP3 | PLPP4 | PLPP5 | PLPP6 | PLPP7 | PLPPR1 | PLPPR2 | PLPPR3 | PLPPR4 | PLPPR5 | PLPPR5-AS1 | PLRG1 | PLS1 | PLS3 | PLSCR1 | PLSCR2 | PLSCR3 | PLSCR4 | PLSCR5 | PLTP | PLUT | PLVAP | PLXDC1 | PLXDC2 | PLXNA1 | PLXNA2 | PLXNA3 | PLXNA4 | PLXNB1 | PLXNB2 | PLXNB3 | PLXNC1 | PLXND1 | PM20D1 | PM20D2 | PMAIP1 | PMCH | PMCHL1 | PMCHL2 | PMEL | PMEPA1 | PMF1 | PMF1-BGLAP | PMFBP1 | PML | PMM1 | PMM2 | PMP2 | PMP22 | PMPCA | PMPCB | PMS1 | PMS2 | PMS2P1