PLAGL1: Key Player in Proteasome System and Neurotransmitter Production

Target Name: PLAGL1

NCBI ID: G5325

PLAGL1: Key Player in Proteasome System and Neurotransmitter Production

PLAGL1 (Proteasome-Lysine-30) is a protein that is expressed in various tissues throughout the body. It is a key player in the proteasome system, which is responsible for breaking down and degrading damaged or unnecessary proteins. PLAGL1 is highly expressed in the brain, and has been implicated in a number of neurological and psychiatric disorders.

One of the key functions of PLAGL1 is its role in the production of neurotransmitters, such as dopamine and serotonin. These neurotransmitters play a crucial role in the brain's communication system, and are involved in a wide range of physiological processes, including mood regulation, appetite, and sleep.

In addition to its role in neurotransmitter production, PLAGL1 is also involved in the regulation of pain. Studies have shown that PLAGL1 is expressed in the pain-producing neurons of the central nervous system, and that it plays a role in the development of pain sensitivity. This suggests that PLAGL1 may be a potential drug target for the treatment of pain disorders.

Another function of PLAGL1 is its role in the regulation of inflammation.PLAGL1 is expressed in the immune cells that are responsible for fighting off infections, and it is involved in the production of a type of immune response called an immune evasion response. This suggests that PLAGL1 may be a potential drug target for the treatment of autoimmune disorders.

PLAGL1 is also involved in the regulation of cell survival. Studies have shown that PLAGL1 is expressed in cancer cells, and that it plays a role in the development and progression of cancer. This suggests that PLAGL1 may be a potential drug target for the treatment of cancer.

In addition to its role in cancer and neurotransmission, PLAGL1 is also involved in the regulation of a wide range of physiological processes in the body. For example, it is involved in the production of the protein involved in the production of collagen, which is important for the formation of skin, hair, and other tissues. PLAGL1 is also involved in the regulation of the production of insulin, a hormone that helps regulate blood sugar levels.

Overall, PLAGL1 is a highly interconnected protein that is involved in a wide range of physiological processes in the body. Its role in the production of neurotransmitters, pain regulation, and inflammation makes it a potential drug target for the treatment of a wide range of disorders. Further research is needed to fully understand the functions of PLAGL1 and its potential as a drug target.

Protein Name: PLAG1 Like Zinc Finger 1

Functions: Acts as a transcriptional activator (PubMed:9722527). Involved in the transcriptional regulation of type 1 receptor for pituitary adenylate cyclase-activating polypeptide

More Common Targets