PIK3C2G: A Protein with Potential as A Drug Target Or Biomarker

Target Name: PIK3C2G

NCBI ID: G5288

Other Name(s): PIK3C2G variant 1 | PIK3C2G variant 3 | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma, transcript variant 3 | Phosphoinositide 3-kinase-C2-gamma | phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide | Phosphatidylinositol 3-kinase C2 domain-containing gamma | Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma | Phosphoinositide-3-kinase, class 2, gamma polypeptide | Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (isoform 1) | PI3K-C2-gamma | MGC163149 | Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide | PtdIns-3-kinase C2 subunit gamma | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma, transcript variant 1 | P3C2G_HUMAN | PI3K-C2GAMMA | phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma | phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma | phosphoinositide-3-kinase, class 2, gamma polypeptide | Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (isoform 3) | PTDINS-3-kinase C2 gamma | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma

PIK3C2G: A Protein with Potential as A Drug Target Or Biomarker

PIK3C2G, also known as PIK3C2G variant 1, is a protein that is expressed in various tissues throughout the body. It is a member of the PIK3C family, which is known for its role in cell signaling. While PIK3C2G is primarily a protein, its functions and interactions with other proteins and molecules are still being fully understood.

The PIK3C2G gene has been identified and its expression has been shown to be highly regulated in various organisms, including humans. Studies have shown that PIK3C2G can play a role in a variety of cellular processes, including cell adhesion, migration, and signaling.

Despite its potential role in cellular signaling, PIK3C2G is still an enigmatic protein. Its functions and interactions with other proteins and molecules are not well understood, and it is not yet clear what the best way to study it is. However, there is a growing interest in PIK3C2G as a potential drug target or biomarker, and a number of research groups are actively exploring its potential role in these areas.

In this article, we will explore the biology and functions of PIK3C2G, with a focus on its potential as a drug target or biomarker. We will discuss the current state of research on PIK3C2G, and the potential implications of its study for the development of new treatments for various diseases.

Biology and Functions of PIK3C2G

PIK3C2G is a member of the PIK3C family, which is known for its role in cell signaling. The PIK3C family consists of four subfamilies: PIK3C, PIK3CA, PIK3CB, and PIK3CAF. These subfamilies have been shown to be involved in a variety of cellular processes , including cell adhesion, migration, and signaling.

PIK3C2G is a 21-kDa protein that is expressed in various tissues throughout the body. It is highly conserved, with a calculated pI of 5.6 and a predicted localization in the cytoplasm. PIK3C2G is involved in a variety of cellular processes, including cell adhesion, migration, and signaling.

One of PIK3C2G's most well-studied functions is its role in cell adhesion. PIK3C2G has been shown to be involved in the formation of tight junctions, which are a type of cell-cell adhesion structure that helps to maintain tissue structure and prevent excessive fluid from Oozing.

In addition to its role in cell adhesion, PIK3C2G is also involved in the regulation of cell migration. Studies have shown that PIK3C2G can inhibit the migration of cancer cells, suggesting that it may have a negative impact on the development and progression of cancer.

PIK3C2G is also involved in a variety of signaling pathways. For example, it has been shown to be involved in the PI3K/Akt signaling pathway, which is involved in a variety of cellular processes, including cell survival and angiogenesis.

Despite its potential role in cellular signaling, PIK3C2G is still an enigmatic protein. Its functions and interactions with other proteins and molecules are not well understood, and it is not yet clear what the best way to study it is.

Potential as a Drug Target or Biomarker

The potential use of PIK3C2G as a drug target or biomarker has generated a significant amount of interest in recent years. Studies have shown that PIK3C2G can be targeted by small molecules, including inhibitors of the PI3K/Akt signaling pathway.

One of the most promising compounds that has been shown to interact with PIK3C2G is a small molecule called U-87120. U-87120 is a potent inhibitor of the PI3K/Akt signaling pathway, and has been shown to inhibit the migration

Protein Name: Phosphatidylinositol-4-phosphate 3-kinase Catalytic Subunit Type 2 Gamma

Functions: Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers (By similarity). May play a role in SDF1A-stimulated chemotaxis (By similarity)

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