PHF23: A Protein with Multiple Functions in Neural Systems (G79142)
PHF23: A Protein with Multiple Functions in Neural Systems
PHF23 (hJUNE-1b) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the HJUNE family of proteins, which are known for their role in cell signaling and development.
PHF23 is a 23-kDa protein that is expressed in the brain, heart, and kidneys. It is a member of the HJUNE family of proteins, which are known for their role in cell signaling and development. PHF23 is highly expressed in the brain, where it is found in the basal ganglia, a part of the nervous system that is responsible for motor function and brain activity.
One of the key functions of PHF23 is its role in the regulation of neural circuits. PHF23 has been shown to play a role in the development and maintenance of neural circuits, as well as the regulation of synaptic plasticity. This means that PHF23 may be a useful drug target for the treatment of a variety of neurological and psychiatric disorders.
Another function of PHF23 is its role in cell signaling and development. PHF23 has been shown to play a role in the regulation of cell proliferation and differentiation, as well as the regulation of cell survival. This means that PHF23 may be a useful biomarker for the assessment of the effectiveness of certain treatments.
In addition to its role in neural circuits and cell signaling, PHF23 is also involved in the regulation of inflammation. PHF23 has been shown to play a role in the regulation of immune cell function, as well as the regulation of inflammation. This means that PHF23 may be a useful target for the treatment of inflammatory disorders.
Overall, PHF23 is a protein that is expressed in various tissues of the body, and it has a variety of functions in neural circuits, cell signaling, and inflammation. As a result, it may be a useful drug target or biomarker for the treatment of a variety of neurological and psychiatric disorders. Further research is needed to fully understand the role of PHF23 in these processes, and to determine the most effective way to use it as a therapeutic agent.
Protein Name: PHD Finger Protein 23
Functions: Acts as a negative regulator of autophagy, through promoting ubiquitination and degradation of LRSAM1, an E3 ubiquitin ligase that promotes autophagy in response to starvation or infecting bacteria
More Common Targets
PHF24 | PHF2P1 | PHF2P2 | PHF3 | PHF5A | PHF6 | PHF7 | PHF8 | PHGDH | PHGR1 | PHIP | PHKA1 | PHKA1-AS1 | PHKA2 | PHKA2-AS1 | PHKB | PHKG1 | PHKG2 | PHLDA1 | PHLDA2 | PHLDA3 | PHLDB1 | PHLDB2 | PHLDB3 | PHLPP1 | PHLPP2 | Phosphatidylinositol 3-kinase (PI3K) | Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) | Phosphatidylinositol 4-Kinase (PI4K) | Phosphatidylinositol 4-Kinase beta (PI4K-beta) | Phosphatidylinositol 4-phosphate 5-kinase | Phosphatidylinositol N-acetylglucosaminyltransferase | Phosphatidylinositol-5-phosphate 4-kinase | PHOSPHO1 | PHOSPHO2 | PHOSPHO2-KLHL23 | Phosphodiesterase | Phosphodiesterase 1 (PDE1) | Phosphodiesterase 6 (PDE6) | Phosphodiesterase 8 (nons | Phosphodiesterase IV (PDE4) | Phosphoglucomutase 5 pseudogene 1 | Phosphoglycerate kinase | Phospholipase A | Phospholipase A2 | Phospholipase A2, Cytosolic | Phospholipase A2, Secretory (sPLA2) | Phospholipase C | Phospholipase D | Phosphorylase kinase | PHOX2A | PHOX2B | PHPT1 | PHRF1 | PHTF1 | PHTF2 | PHYH | PHYHD1 | PHYHIP | PHYHIPL | PHYKPL | PI15 | PI16 | PI3 | PI4K2A | PI4K2B | PI4KA | PI4KAP1 | PI4KAP2 | PI4KB | PIANP | PIAS1 | PIAS2 | PIAS3 | PIAS4 | PIBF1 | PICALM | PICART1 | PICK1 | PICSAR | PID1 | PIDD1 | PIERCE1 | PIERCE2 | PIEZO1 | PIEZO2 | PIF1 | PIFO | PIGA | PIGB | PIGBOS1 | PIGC | PIGF | PIGG | PIGH | PIGK | PIGL | PIGM | PIGN | PIGO