PFKFB1: A Potential Drug Target for Cancer (G5207)

Target Name: PFKFB1

NCBI ID: G5207

PFKFB1: A Potential Drug Target for Cancer

Phosphofructo-2-kinase (PFKFB1) is a protein that plays a crucial role in cellular metabolism. It is a key enzyme in the glycolytic pathway, which is the process by which glucose is broken down to produce energy. PFKFB1 is highly conserved and has been identified as a potential drug target in the field of cancer.

The PFKFB1 enzyme is found in most eukaryotic cells and is responsible for the catalytic activity of the PFKFB1 kinase. The PFKFB1 kinase is a critical enzyme in the glycolytic pathway and is involved in the breakdown of glucose to produce energy. It is highly conserved and has been identified as a potential drug target in the field of cancer.

PFKFB1 has been shown to be involved in the regulation of cellular processes such as cell growth, apoptosis, and inflammation. It has also been shown to play a role in the development and progression of several diseases, including cancer.

One of the key functions of PFKFB1 is its role in cell death. When a cell is no longer able to divide or repair itself, it undergoes apoptosis. PFKFB1 is involved in the regulation of apoptosis and has been shown to play a role in the execution of this process.

In addition to its role in cell death, PFKFB1 is also involved in the regulation of cell growth. It has been shown to play a role in the regulation of cell cycle progression and has been shown to be involved in the development of cancer.

PFKFB1 has also been shown to be involved in the regulation of inflammation. It has been shown to play a role in the production of pro-inflammatory cytokines and has been shown to contribute to the development of inflammatory diseases.

In conclusion, PFKFB1 is a protein that plays a crucial role in cellular metabolism and has been shown to be involved in the regulation of cell death, growth, and inflammation. As a result, it is a potential drug target in the field of cancer and has been identified as a potential biomarker for several diseases. Further research is needed to fully understand the role of PFKFB1 in cellular processes and its potential as a drug target.

Protein Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

Functions: Synthesis and degradation of fructose 2,6-bisphosphate

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