PGAP4: A Potential Drug Target for PDZ Family of Proteins (G84302)

Target Name: PGAP4

NCBI ID: G84302

PGAP4: A Potential Drug Target for PDZ Family of Proteins

PGAP4 (C9orf125) is a protein that is expressed in various tissues throughout the body. It is a member of the PDZ family of proteins, which are known for their role in cell signaling and development. While PGAP4 is not a well-studied protein, research has shown that it is involved in several cellular processes, including cell adhesion, migration, and survival.

One of the most promising aspects of PGAP4 is its potential as a drug target. The PDZ family of proteins has been shown to play a critical role in numerous diseases, including cancer, neurodegenerative diseases, and developmental disorders. Therefore, PGAP4 may be a promising target for new therapies.

PGAP4 is a 21-kDa protein that is expressed in various tissues, including brain, heart, liver, and muscle. It is a member of the PDZ family of proteins, which are known for their role in cell signaling and development. The PDZ family includes several other proteins, including ZF21F1, ZF21A1, ZF21B1, ZF21C1, and ZF21D1. These proteins are involved in a variety of cellular processes, including cell adhesion, migration, and survival.

PGAP4 is involved in several cellular processes that are important for normal development and function. For example, it is involved in the regulation of cell adhesion, which is critical for the development and maintenance of tissues and organs. PGAP4 has been shown to play a role in the regulation of cell adhesion in various tissues, including the brain.

PGAP4 is also involved in the regulation of cell migration, which is critical for the development and organization of tissues and organs. It has been shown to play a role in the regulation of cell migration in various tissues, including the brain.

PGAP4 is also involved in the regulation of cell survival, which is critical for the development and maintenance of tissues and organs. It has been shown to play a role in the regulation of cell survival in various tissues, including the brain.

Despite the promising potential of PGAP4 as a drug target, research on the protein has been limited. There are currently no known drugs that are specifically designed to target PGAP4. However, research is ongoing to determine the role of PGAP4 in various cellular processes and to identify potential drug targets.

In conclusion, PGAP4 is a protein that is expressed in various tissues throughout the body. It is a member of the PDZ family of proteins, which are known for their role in cell signaling and development. While PGAP4 is not a well-studied protein, research has shown that it is involved in several cellular processes, including cell adhesion, migration, and survival. Therefore, PGAP4 may be a promising target for new therapies. Further research is needed to fully understand the role of PGAP4 and to identify potential drug targets.

Protein Name: Post-GPI Attachment To Proteins GalNAc Transferase 4

Functions: Golgi-resident glycosylphosphatidylinositol (GPI)-N-acetylgalactosamine transferase involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins (PubMed:29374258). Required for the initial step of GPI-GalNAc biosynthesis, transfers GalNAc to GPI in the Golgi after fatty acid remodeling by PGAP2 (PubMed:29374258)

More Common Targets