PEG13: A Protein Involved in Neurological Disorders (G359809)

Target Name: PEG13

NCBI ID: G359809

Other Name(s): Paternally expressed 13 | paternally expressed 13

PEG13: A Protein Involved in Neurological Disorders

PEG13 (Paternally expressed 13) is a protein that is expressed in the brain and other tissues, and has been shown to play a role in the development and progression of a number of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and depression.

The protein PEG13 is produced by a process called paternally expressed gene, which means that it is created by the expression of a gene that is present in the cell's DNA, but is not typically expressed. This gene is typically expressed in the brain, and is thought to play a role in the development and maintenance of the brain's unique structure and function.

PEG13 has been shown to interact with a number of different proteins, including the protein tau, which is thought to play a role in the development of Alzheimer's disease. The interaction between PEG13 and tau has been shown to contribute to the development of the protein aggregates that are thought to be responsible for the cognitive decline and other symptoms of Alzheimer's disease.

In addition to its role in the development of Alzheimer's disease, PEG13 has also been shown to be involved in the treatment of other neurological and psychiatric disorders. For example, studies have shown thatPEG13 can be used to deliver small molecules to the brain, which can help to reduce the amount of tau protein that accumulates and may help to slow the progression of neurodegeneration.

PEG13 is also a potential drug target, as it has been shown to interact with a number of different proteins, including the protein PSD-90, which is a protein that is thought to play a role in the development of depression. Studies have shown that the PSD-90 protein is expressed in the brain and that it interacts with PEG13, which suggests that it may be a useful target for the treatment of depression.

In conclusion, PEG13 is a protein that has been shown to play a role in the development and progression of a number of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and depression. Its interaction with the protein tau and its potential as a drug target make it an attractive target for further research and development.

Protein Name: Paternally Expressed 13

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