Target Name: PEX11G
NCBI ID: G92960
Other Name(s): peroxin-11C | Peroxisomal biogenesis factor 11 gamma, transcript variant 2 | Protein PEX11 homolog gamma | PEX11G variant 2 | peroxin Pex11p gamma | peroxisomal biogenesis factor 11G | protein PEX11 homolog gamma | Peroxisomal membrane protein 11C (isoform 2) | Peroxisomal biogenesis factor 11C | Peroxisomal biogenesis factor 11 gamma, transcript variant 1 | peroxisomal biogenesis factor 11C | PEX11gamma | Peroxisomal membrane protein 11G | Peroxisomal membrane protein 11C (isoform 1) | Peroxisomal membrane protein 11C | Peroxin Pex11p gamma | PEX11-gamma | Peroxin-11C | Pex11pgamma | PX11C_HUMAN | peroxisomal biogenesis factor 11 gamma | PEX11C | PEX11G variant 1 | Peroxisomal biogenesis factor 11G

PEX11G: A Unique Peroxin Protein with Potential Clinical Applications

Peroxin-11G (PEX11G) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the peroxin family of proteins, which are known for their ability to generate reactive oxygen species (ROS) that can cause damage to cellular components if not properly managed.

PEX11G is unique among peroxin proteins in that it is expressed in the brain, where it is involved in the detoxification of harmful ROS generated by cellular metabolism. It is also one of the only peroxins that are known to be expressed in the brain, which suggests that it may play an important role in the brain's defense against oxidative stress.

In addition to its expression in the brain, PEX11G is also known for its role in the regulation of cellular signaling pathways. It has been shown to play a role in the regulation of angiogenesis, which is the process by which new blood vessels are formed in the body, and has been linked to the development of various diseases, including cancer.

PEX11G is also of interest as a potential drug target. Its unique expression in the brain and its involvement in cellular signaling pathways make it an attractive target for small molecule inhibitors. Several compounds have been shown to interact with PEX11G and to inhibit its activity, which suggests that these compounds may have therapeutic potential.

In addition to its potential as a drug target, PEX11G is also of interest as a biomarker. Its expression in various tissues and its involvement in cellular signaling pathways make it a potential candidate for use as a diagnostic or predictive marker for a variety of diseases.

Overall, PEX11G is a protein that is unique among its class and has the potential to be a drug target or biomarker. Further research is needed to fully understand its role in the body and its potential clinical applications.

Protein Name: Peroxisomal Biogenesis Factor 11 Gamma

Functions: Promotes membrane protrusion and elongation on the peroxisomal surface

More Common Targets

PEX12 | PEX13 | PEX14 | PEX16 | PEX19 | PEX2 | PEX26 | PEX3 | PEX5 | PEX5L | PEX5L-AS2 | PEX6 | PEX7 | PF4 | PF4V1 | PFAS | PFDN1 | PFDN2 | PFDN4 | PFDN5 | PFDN6 | PFKFB1 | PFKFB2 | PFKFB3 | PFKFB4 | PFKL | PFKM | PFKP | PFN1 | PFN1P2 | PFN1P3 | PFN1P4 | PFN1P6 | PFN1P8 | PFN2 | PFN3 | PFN4 | PGA3 | PGA4 | PGA5 | PGAM1 | PGAM1P5 | PGAM1P7 | PGAM1P8 | PGAM2 | PGAM4 | PGAM5 | PGAM5-KEAP1-NRF2 Complex | PGAP1 | PGAP2 | PGAP3 | PGAP4 | PGAP6 | PGBD1 | PGBD2 | PGBD3 | PGBD4 | PGBD4P3 | PGBD4P4 | PGBD5 | PGBP | PGC | PGD | PGF | PGGHG | PGGT1B | PGK1 | PGK1P2 | PGK2 | PGLS | PGLYRP1 | PGLYRP2 | PGLYRP3 | PGLYRP4 | PGM1 | PGM2 | PGM2L1 | PGM3 | PGM5 | PGM5-AS1 | PGM5P2 | PGM5P4 | PGM5P4-AS1 | PGP | PGPEP1 | PGPEP1L | PGR | PGR-AS1 | PGRMC1 | PGRMC2 | PGS1 | PHACTR1 | PHACTR2 | PHACTR3 | PHACTR3-AS1 | PHACTR4 | PHAF1 | PHAX | PHB1 | PHB1P1