Target Name: PDE7A
NCBI ID: G5150
Other Name(s): Phosphodiesterase PDE7A | PDE7A variant 3 | HCP1 | PDE7A_HUMAN | PDE7A variant 1 | PDE7A1 | PDE7 | Phosphodiesterase isozyme 7 | PDE7A2 | Phosphodiesterase 7A | phosphodiesterase isozyme 7 | TM22 | ph

Phosphodiesterase PDE7A: A Protein with Multiple Roles in Cellular Signaling

Phosphodiesterase PDE7A is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It plays a critical role in the regulation of cellular signaling pathways, and is involved in a wide range of physiological processes.

One of the key functions of PDE7A is its role in the regulation of neurotransmitter release from nerve terminals. This is important for the proper functioning of the brain and for the treatment of various neurological disorders.

In addition to its role in neurotransmitter release, PDE7A is also involved in the regulation of ion channels in the brain. This is important for the proper functioning of neural circuits and for the treatment of various neurological disorders.

PDE7A is a potential drug target for a variety of neurological disorders, including Alzheimer's disease, Parkinson's disease, and epilepsy. It is also a potential biomarker for these disorders, as its levels may be affected by the progression of these diseases.

In addition to its potential clinical applications, PDE7A is also of interest to researchers as a study protein. Researchers are interested in understanding its structure and function, as well as its role in various cellular signaling pathways.

Overall, PDE7A is a complex protein that plays a critical role in the regulation of cellular signaling pathways. Its functions in neurotransmitter release and ion channel regulation make it an attractive target for drug development and research into the underlying mechanisms of various neurological disorders.

Protein Name: Phosphodiesterase 7A

Functions: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:8389765, PubMed:9195912, PubMed:19350606). May have a role in muscle signal transduction (PubMed:9195912)

More Common Targets

PDE7B | PDE7B-AS1 | PDE8A | PDE8B | PDE9A | PDE9A-AS1 | PDF | PDGFA | PDGFA-DT | PDGFB | PDGFC | PDGFD | PDGFRA | PDGFRB | PDGFRL | PDHA1 | PDHA2 | PDHB | PDHX | PDIA2 | PDIA3 | PDIA3P1 | PDIA4 | PDIA5 | PDIA6 | PDIK1L | PDILT | PDK1 | PDK2 | PDK3 | PDK4 | PDLIM1 | PDLIM1P4 | PDLIM2 | PDLIM3 | PDLIM4 | PDLIM5 | PDLIM7 | PDP1 | PDP2 | PDPK1 | PDPK2P | PDPN | PDPR | PDPR2P | PDRG1 | PDS5A | PDS5B | PDS5B-DT | PDSS1 | PDSS2 | PDX1 | PDXDC1 | PDXDC2P-NPIPB14P | PDXK | PDXP | PDYN | PDYN-AS1 | PDZD11 | PDZD2 | PDZD4 | PDZD7 | PDZD8 | PDZD9 | PDZK1 | PDZK1IP1 | PDZK1P1 | PDZPH1P | PDZRN3 | PDZRN3-AS1 | PDZRN4 | PEA15 | PEAK1 | PEAK3 | PEAR1 | PeBoW complex | PEBP1 | PEBP1P2 | PEBP4 | PECAM1 | PECR | PEDS1 | PEDS1-UBE2V1 | PEF1 | PEG10 | PEG13 | PEG3 | PEG3-AS1 | PELATON | PELI1 | PELI2 | PELI3 | PELO | PELP1 | PELP1-DT | PEMT | PENK | PENK-AS1 | PEPD | Peptidyl arginine deiminase (PAD)