ANKRD7: A Potential Drug Target and Biomarker (G56311)
ANKRD7: A Potential Drug Target and Biomarker
Introduction
Ankyrin repeat domains (ANKRDs) are a class of non-coding DNA sequences that have been identified in various organisms as being involved in a wide range of cellular processes. One of the most well-studied ANKRDs is ANKRD7, which is located in the gene Ankyrin C (ANKRCD). ANKRD7 has been shown to play a crucial role in the regulation of various cellular processes, including cell signaling, DNA replication, and metabolism. In this article, we will explore the potential implications of ANKRD7 as a drug target and biomarker.
The ANKRD7 Gene
The ANKRD7 gene is located at position 6.3 kb on chromosome 11q22. It consists of 214 amino acid residues and has a calculated pI of 5.5. ANKRD7 is a member of the ANKRD family, which includes several other non-coding DNA sequences that share a similar structure and function. The ANKRD family has been identified in various organisms, including bacteria, archaea, and eukaryotes.
The ANKRD7 gene is expressed in various tissues and cells of the human body, including the brain, heart, liver, and kidney. It has been shown to be involved in the regulation of various cellular processes, including cell signaling, DNA replication, and metabolism . For example, ANKRD7 has been shown to play a role in the regulation of the protein p21, which is involved in the T-cell receptor signaling pathway.
The Potential Role of ANKRD7 as a Drug Target
The ANKRD7 gene has been identified as a potential drug target due to its involvement in various cellular processes that are associated with the development and progression of various diseases. One of the potential mechanisms by which ANKRD7 can be targeted is through its role in cell signaling. ANKRD7 has been shown to play a role in the regulation of the T-cell receptor signaling pathway, which is involved in the immune response.
The T-cell receptor is a protein that is involved in the regulation of T-cell development and function. It consists of a transmembrane domain and a cytoplasmic tail that contains a co-factor protein called Fc. The T-cell receptor signaling pathway is involved in the regulation of various cellular processes, including cell growth, apoptosis, and inflammation.
Research has shown that ANKRD7 is involved in the regulation of the T-cell receptor signaling pathway through its role in the regulation of the protein p21. P21 is a transcription factor that is involved in the regulation of various cellular processes, including cell growth, apoptosis , and DNA replication. Studies have shown that ANKRD7 has been shown to play a role in the regulation of p21 through its interaction with the protein p21 itself.
In addition to its role in cell signaling, ANKRD7 has also been shown to be involved in the regulation of DNA replication. DNA replication is a critical process that is involved in the regulation of cell growth and development. ANKRD7 has been shown to play a role in the regulation of DNA replication through its interaction with the protein DNAT2.
The Potential Role of ANKRD7 as a Biomarker
The ANKRD7 gene has also been shown to be involved in the regulation of various cellular processes that can be used as biomarkers for the diagnosis and treatment of various diseases. One of the potential applications of ANKRD7 as a biomarker is its involvement in the regulation of cancer cell growth and
Protein Name: Ankyrin Repeat Domain 7
More Common Targets
ANKRD9 | ANKS1A | ANKS1B | ANKS3 | ANKS4B | ANKS6 | ANKUB1 | ANKZF1 | ANLN | Annexin | ANO1 | ANO10 | ANO2 | ANO3 | ANO4 | ANO5 | ANO6 | ANO7 | ANO7L1 | ANO8 | ANO9 | Anoctamin | ANOS1 | ANOS2P | ANP32A | ANP32A-IT1 | ANP32AP1 | ANP32B | ANP32C | ANP32D | ANP32E | ANPEP | ANTKMT | ANTXR1 | ANTXR2 | ANTXRL | ANTXRLP1 | ANXA1 | ANXA10 | ANXA11 | ANXA13 | ANXA2 | ANXA2P1 | ANXA2P2 | ANXA2P3 | ANXA2R | ANXA2R-AS1 | ANXA2R-OT1 | ANXA3 | ANXA4 | ANXA5 | ANXA6 | ANXA7 | ANXA8 | ANXA8L1 | ANXA8L2 | ANXA9 | AOAH | AOC1 | AOC2 | AOC3 | AOC4P | AOPEP | AOX1 | AOX2P | AP-1 Transcription Factor Complex | AP1AR | AP1B1 | AP1B1P1 | AP1G1 | AP1G2 | AP1M1 | AP1M2 | AP1S1 | AP1S2 | AP1S3 | AP2A1 | AP2A2 | AP2B1 | AP2M1 | AP2S1 | AP3B1 | AP3B2 | AP3D1 | AP3M1 | AP3M2 | AP3S1 | AP3S2 | AP4B1 | AP4B1-AS1 | AP4E1 | AP4M1 | AP4S1 | AP5B1 | AP5M1 | AP5S1 | AP5Z1 | APAF1 | APBA1 | APBA2