Unlocking The Regulatory Role of GATAD1: A Zinc Finger Domain-Containing Protein
Unlocking The Regulatory Role of GATAD1: A Zinc Finger Domain-Containing Protein
GATA zinc finger domain-containing protein 1 (GATAD1) is a protein that is expressed in almost all eukaryotic cells and plays an important regulatory role in many biological processes. The gene coding region of GATAD1 contains a zinc finger domain, and its unique structural characteristics make it a very attractive research object.
The biological functions of GATAD1 include regulating gene expression, cell proliferation and apoptosis, and chromatin structure and function during the cell cycle. In the cell cycle, GATAD1 is expressed in G1, S and G2 phases and plays an important role in mitosis. The expression level of GATAD1 is highest in S phase, because at this stage, cells need to prepare for DNA replication and chromosome segregation.
GATAD1 is also closely related to many important biological processes, including cell proliferation, apoptosis, and cell cycle regulation. For example, GATAD1 is highly expressed in certain types of cancers, including lung cancer, liver cancer, breast cancer, etc. Therefore, GATAD1 can be used as a potential drug target or biomarker for predicting disease risk and treatment response.
The structure and function of GATAD1 also make it a very attractive research target. The zinc finger domain of GATAD1 is a unique chemical domain consisting of four helices. This domain can bind to phosphate groups in DNA molecules, thereby regulating the structure and function of DNA. The zinc finger domain of GATAD1 can also bind to other proteins to form different complexes, and these complexes may affect the biological functions of GATAD1.
In addition, the biological function of GATAD1 is also related to its expression level. In certain types of cancer, GATAD1 expression is higher, including lung cancer, liver cancer, breast cancer, etc. Therefore, by detecting the expression level of GATAD1, disease risk can be predicted and can also be used as a monitoring indicator of treatment response.
As a very attractive research object, GATAD1 plays an important regulatory role in biological processes. The unique chemical domain of its zinc finger domain and its ability to bind to DNA make GATAD1 a very potential drug target or biomarker. By studying the biological functions and structural characteristics of GATAD1, we can provide new treatments for
Protein Name: GATA Zinc Finger Domain Containing 1
Functions: Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3)
More Common Targets
GATAD2A | GATAD2B | GATB | GATC | GATD1 | GATD1-DT | GATD3 | GATM | GATOR1 Complex | GAU1 | GBA1 | GBA2 | GBA3 | GBAP1 | GBE1 | GBF1 | GBGT1 | GBP1 | GBP1P1 | GBP2 | GBP3 | GBP4 | GBP5 | GBP6 | GBP7 | GBX1 | GBX2 | GC | GCA | GCAT | GCC1 | GCC2 | GCC2-AS1 | GCDH | GCFC2 | GCG | GCGR | GCH1 | GCHFR | GCK | GCKR | GCLC | GCLM | GCM1 | GCM2 | GCN1 | GCNA | GCNT1 | GCNT1P3 | GCNT2 | GCNT3 | GCNT4 | GCNT7 | GCOM1 | GCSAM | GCSAML | GCSAML-AS1 | GCSH | GCSHP3 | GCSIR | GDA | GDAP1 | GDAP1L1 | GDAP2 | GDE1 | GDF1 | GDF10 | GDF11 | GDF15 | GDF2 | GDF3 | GDF5 | GDF6 | GDF7 | GDF9 | GDI1 | GDI2 | GDI2P1 | GDNF | GDNF Family Receptor alpha | GDNF-AS1 | GDPD1 | GDPD2 | GDPD3 | GDPD4 | GDPD5 | GDPGP1 | GEM | GEMIN2 | GEMIN4 | GEMIN5 | GEMIN6 | GEMIN7 | GEMIN8 | GEMIN8P1 | GEMIN8P4 | GEN1 | general transcription factor IIF (TFIIF) | General transcription factor IIH | Geranylgeranyl transferase