GCHFR: A Protein Interacting with Multiple Neurotransmitters (G2644)

Target Name: GCHFR

NCBI ID: G2644

GCHFR: A Protein Interacting with Multiple Neurotransmitters

GCHFR (HsT16933) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the G protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a critical role in cellular signaling.

GCHFR is known for its role in the regulation of ion channels, which are critical for the proper functioning of various physiological processes in the body. In particular, GCHFR is involved in the regulation of neurotransmitter receptors, which are responsible for transmitting signals from the brain to other parts of the body.

One of the unique features of GCHFR is its ability to interact with multiple neurotransmitter receptors, making it a potential drug target. Studies have shown that GCHFR can interact with a wide range of neurotransmitters, including dopamine, serotonin, and endocannabinoids.

In addition to its role in neurotransmission, GCHFR is also involved in the regulation of inflammation and pain. Studies have shown that GCHFR is involved in the regulation of the immune response and that it can modulate pain perception.

GCHFR is also a potential biomarker for several diseases, including cancer and neurodegenerative disorders. Studies have shown that GCHFR is overexpressed in various types of cancer, including breast, ovarian, and colorectal cancer. Similarly, GCHFR has also been shown to be involved in the development and progression of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease.

GCHFR is also a potential therapeutic target for several diseases, including depression and anxiety. Studies have shown that GCHFR is involved in the regulation of mood and that it can modulate anxiety-like behavior.

In conclusion, GCHFR is a protein that is involved in a wide range of physiological processes in the body. Its role in neurotransmission, inflammation, and pain regulation makes it a potential drug target and a promising biomarker for several diseases. Further research is needed to fully understand the role of GCHFR in the regulation of these processes and to develop effective treatments for the associated conditions.

Protein Name: GTP Cyclohydrolase I Feedback Regulator

Functions: Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine

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