Study of GCC2 as A Potential Drug Target Or Biomarker (G9648)

Target Name: GCC2

NCBI ID: G9648

Study of GCC2 as A Potential Drug Target Or Biomarker

GCC2 (Ranbp2l4) is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer. Its unique genetic makeup and expression patterns have made it an attractive target for researchers to study.

GCC2 is a non-coding RNA molecule that is located on chromosome 6p21. It is a part of the RANBP2 gene family, which is known for its role in cell signaling and development. The RANBP2 genes are characterized by the presence of a specific intron that is usually excluded in RNA processing, resulting in a truncated protein that is only expressed in the cytoplasm.

GCC2 is expressed in a variety of tissues and cells, including the brain, heart, and cancer cells. Its expression levels vary depending on the specific cell type and the environment in which it is found. One of the most interesting aspects of GCC2 is its ability to be targeted by small molecules, which has led to its potential as a drug.

GCC2 has been shown to play a role in several diseases, including cancer. For example, studies have shown that high levels of GCC2 are associated with poor prognosis in patients with pancreatic cancer, a particularly aggressive form of the disease. Additionally, GCC2 has been shown to be overexpressed in a variety of cancer types, including breast, lung, and ovarian cancer.

In addition to its potential as a drug target, GCC2 has also been identified as a potential biomarker. Its expression levels can be easily measured and correlated with disease outcomes, making it a promising tool for the development of new diagnostic tests or biomarkers. This is particularly important given the need for more targeted and effective therapies for cancer.

GCC2 has also been shown to play a role in cell signaling and development. It is a part of a signaling pathway that is involved in cell migration, invasion, and angiogenesis, which is the process by which new blood vessels are formed in tumors. Additionally , GCC2 has been shown to be involved in cell apoptosis, which is the process by which cells die when they have reached a certain level of stress or damage.

GCC2 has also been shown to be involved in the regulation of cellular processes that are important for normal development and function. For example, studies have shown that GCC2 is involved in the regulation of cell cycle progression, which is the process by which cells grow and divide, and in the regulation of cell apoptosis, which is the process by which cells die when they have reached a certain level of stress or damage.

In conclusion, GCC2 is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer. Its unique genetic makeup and expression patterns have made it an attractive target for researchers to study. Further research is needed to fully understand the role of GCC2 in cell signaling and development, as well as its potential as a drug or biomarker.

Protein Name: GRIP And Coiled-coil Domain Containing 2

Functions: Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2

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