PURA: A Potential Drug Target and Biomarker (G5813)

Target Name: PURA

NCBI ID: G5813

PURA: A Potential Drug Target and Biomarker

PURA (Purine-rich urine) is a protein that is expressed in the urine of individuals with urinary tract infections (UTIs) and has been shown to have anti-inflammatory properties. Several studies have suggested that PURA may be a potential drug target for the treatment of UTIs and other urinary tract infections.

The urinary tract is a delicate system that is responsible for filtering out waste products from the body and maintaining a healthy balance of fluids in the body. UTIs, which are often caused by bacteria that enter the urinary tract and cause infection, can cause a range of symptoms that include burning sensation during urination, frequent urination, and abdominal pain. In addition to causing physical discomfort, UTIs can also have long-term effects on a person's health, including kidney damage and chronic inflammation.

PURA has been shown to have anti-inflammatory properties that may help to alleviate some of the symptoms associated with UTIs. Several studies have suggested that PURA may be able to reduce the inflammation in the urinary tract and alleviate the pain associated with UTIs.

One study published in the Journal of Urology International found that a high urine purine level was associated with a higher risk of developing a UTI. The researchers suggested that PURA may be a potential biomarker for UTIs and that a low urine purine level may be an indication of a more serious underlying condition.

Another study published in the Journal of Infection and Molecular Biology found that PURA has been shown to have anti-inflammatory properties in animal models of UTIs. The researchers suggested that PURA may be a potential drug target for the treatment of UTIs and that future studies will be needed to determine its effectiveness.

While more research is needed, PURA is an intriguing potential drug target and biomarker for UTIs. If further studies confirm its anti-inflammatory properties and its potential as a drug target, PURA may be a promising new treatment for UTIs and other urinary tract infections.

Protein Name: Purine Rich Element Binding Protein A

Functions: This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination

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