MIR451B: A Potential Drug Target and Biomarker (G100616273)
MIR451B: A Potential Drug Target and Biomarker
Mir451B, a protein encoded by the human gene Mir451B, is a non-coding RNA molecule that has been shown to play a role in various biological processes. The Mir451B gene has been identified as a potential drug target and biomarker for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
The Mir451B protein is a key regulator of microRNA (miRNA) expression, a class of non-coding RNAs that play a crucial role in post-transcriptional gene regulation. miRNA molecules are designed to target specific mRNAs for degradation or translation, and are involved in a wide range of cellular processes, including cell growth, differentiation, and survival.
Mir451B has been shown to play a negative role in the regulation of miRNA expression in various organisms, including humans. Studies have shown that Mir451B can interact with the miR-202 complex, a known regulator of miRNA expression, and can inhibit its activity. This interaction between Mir451B and miR-202 highlights the potential of Mir451B as a drug target.
In addition to its role in miRNA regulation, Mir451B has also been shown to play a role in the regulation of gene expression and cellular processes. Studies have shown that Mir451B can interact with various cellular signaling pathways, including TGF-β, PI3K, and NF-kappa-B. This interaction between Mir451B and these signaling pathways suggests that it may be involved in the regulation of cellular processes that are important for human health and disease.
The potential drug target for Mir451B is based on its role in the regulation of miRNA expression and its interaction with miR-202. miRNA-based therapies have been shown to be effective in treating a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Therefore, targeting Mir451B as a drug candidate could potentially lead to new treatments for a variety of diseases.
In conclusion, Mir451B is a protein that has been shown to play a role in various biological processes, including the regulation of miRNA expression and cellular signaling pathways. Its potential as a drug target and biomarker makes it an attractive candidate for further research and development. Further studies are needed to fully understand the role of Mir451B in disease and to develop effective treatments based on its potential as a drug.
Protein Name: MicroRNA 451b
More Common Targets
MIR452 | MIR4520-1 | MIR4520-2 | MIR4521 | MIR4524A | MIR4524B | MIR4525 | MIR4526 | MIR4527 | MIR4527HG | MIR4529 | MIR4530 | MIR4531 | MIR4533 | MIR4534 | MIR4535 | MIR4536-1 | MIR4536-2 | MIR4537 | MIR4538 | MIR4539 | MIR454 | MIR4540 | MIR455 | MIR4632 | MIR4633 | MIR4634 | MIR4635 | MIR4638 | MIR4639 | MIR4640 | MIR4641 | MIR4642 | MIR4644 | MIR4645 | MIR4646 | MIR4647 | MIR4648 | MIR4649 | MIR4650-1 | MIR4650-2 | MIR4651 | MIR4652 | MIR4653 | MIR4655 | MIR4656 | MIR4657 | MIR4658 | MIR4659A | MIR4659B | MIR466 | MIR4660 | MIR4661 | MIR4662A | MIR4663 | MIR4664 | MIR4665 | MIR4666A | MIR4666B | MIR4667 | MIR4668 | MIR4669 | MIR4670 | MIR4671 | MIR4672 | MIR4673 | MIR4674 | MIR4675 | MIR4676 | MIR4677 | MIR4679-1 | MIR4679-2 | MIR4680 | MIR4681 | MIR4684 | MIR4685 | MIR4686 | MIR4687 | MIR4688 | MIR4689 | MIR4690 | MIR4691 | MIR4692 | MIR4693 | MIR4694 | MIR4695 | MIR4697 | MIR4697 host gene (non-protein coding) | MIR4698 | MIR4699 | MIR4700 | MIR4701 | MIR4703 | MIR4704 | MIR4706 | MIR4707 | MIR4708 | MIR4709 | MIR4711 | MIR4712
