SNORA7B: A Potential Drug Target and Biomarker (G677797)

Target Name: SNORA7B

NCBI ID: G677797

Other Name(s): Small nucleolar RNA, H/ACA box 7B | small nucleolar RNA, H/ACA box 7B | ACA7B

SNORA7B: A Potential Drug Target and Biomarker

Small nucleolar RNA (snRNA), also known as H/ACA box 7B (H/ACA-7B), is a non-coding RNA molecule that plays a crucial role in the regulation of gene expression in eukaryotic cells. It is a part of the 7B class of snRNAs, which are known for their ability to interact with the protein forskinner complex (SP7) and the A-type Fe2+-dependent extension of the binding protein (APEX). One of the unique features of H/ACA-7B is its ability to interact with the SP7 protein and the APEX protein, which are both known to play important roles in the regulation of gene expression.

H/ACA-7B is a 24-nt RNA molecule that contains a highly conserved H/ACA-like domain and a unique 7' end that consists of a single AUG and a GUG. It is expressed in a variety of tissues and cells, including muscle, heart, liver, and brain, and is involved in the regulation of gene expression in these organisms.

One of the most exciting aspects of H/ACA-7B is its potential as a drug target. The H/ACA-7B protein has been shown to play a role in the regulation of muscle growth and development, and it is thought to be involved in the regulation of muscle protein synthesis. Additionally, H/ACA-7B has also been shown to be involved in the regulation of cell apoptosis, which is the process by which cells die when they have reached a certain level of dysfunction.

Another potential application of H/ACA-7B as a drug target is its role in the regulation of inflammation. H/ACA-7B has been shown to play a role in the regulation of the production of pro-inflammatory cytokines, such as TNF- 伪 and IL-1尾. Additionally, H/ACA-7B has also been shown to play a role in the regulation of the production of anti-inflammatory cytokines, such as IL-10.

In conclusion, SNORA7B is a small nucleolar RNA molecule that is involved in the regulation of gene expression in eukaryotic cells. It is a potential drug target due to its role in the regulation of muscle growth and development, cell apoptosis, and inflammation. Further research is needed to fully understand the role of H/ACA-7B in these processes and to develop effective treatments.

Protein Name: Small Nucleolar RNA, H/ACA Box 7B

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