Target Name: SNORD114-7
NCBI ID: G767583
Other Name(s): Small nucleolar RNA, C/D box 114-7 | small nucleolar RNA, C/D box 114-7 | 14q(II-7)

SNORD114-7: A Potential Drug Target and Biomarker for Small Nucleolar RNA

Small nucleolar RNA (snRNA) is a non-coding RNA molecule that plays a critical role in the regulation of gene expression in eukaryotic cells. One of the key functions of snRNA is to interact with small nucleolar RNA (snoRNA) processing modification system, which is responsible for modifying the stability and localization of snRNAs. C/D box 114-7 is a specific snRNA that is expressed in various tissues and cells and has been shown to play important roles in regulating gene expression.

The C/D box 114-7 is a small RNA molecule that is expressed in various tissues and cells. It is characterized by a conserved core structure that consists of a 19-nt stem-loop and a 30-nt C/D loop. The C/D loop is the region of the snRNA that interacts with the small nucleolar RNA (snoRNA) processing machinery, which is responsible for modifying the stability and localization of snRNAs.

Studies have shown that C/D box 114-7 is involved in a variety of cellular processes, including cell growth, apoptosis, and transcriptional regulation. For example, studies have shown that overexpression of C/D box 114-7 can lead to increased cell proliferation and enhanced cancer cell transformation. Additionally, C/D box 114-7 has been shown to play important roles in regulating cell apoptosis, which is a critical process that helps maintain tissue homeostasis and contributes to the development and progression of diseases.

Furthermore, C/D box 114-7 has also been shown to be involved in transcriptional regulation. Studies have shown that C/D box 114-7 can interact with various DNA-binding proteins and that this interaction can modulate gene expression. For example , studies have shown that C/D box 114-7 can interact with the transcription factor p360 and that this interaction can modulate the expression of genes involved in cell adhesion, migration and invasion.

Given the critical role that C/D box 114-7 plays in various cellular processes, it is a promising target for drug development. Studies have shown that various small molecules, including small molecules that mimic the activity of p360, have the potential to inhibit the activity of C/D box 114-7 and inhibit its ability to interact with DNA-binding proteins. Therefore, C/D box 114-7 may be a promising drug target for the treatment of various diseases.

In addition to its potential as a drug target, C/D box 114-7 is also a potential biomarker. Studies have shown that the expression of C/D box 114-7 is regulated by various factors, including DNA damage, cellular stress and hormonal changes. Therefore, the level of C/D box 114-7 expression can be used as a biomarker for a variety of diseases, including cancer, neurodegenerative diseases and cardiovascular diseases.

In conclusion, C/D box 114-7 is a small RNA molecule that is expressed in various tissues and cells and plays a critical role in the regulation of gene expression in eukaryotic cells. The C/D loop is the region of the snRNA that interacts with the small nucleolar RNA (snoRNA) processing machinery and is involved in a variety of cellular processes, including cell growth, apoptosis and transcriptional regulation. As a result, C/D box 114-7 is a promising target for drug development and a potential biomarker for the treatment of various diseases.

Protein Name: Small Nucleolar RNA, C/D Box 114-7

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