FAM133DP: A Potential Drug Target and Biomarker for Family with Sequence Similarity 133

Target Name: FAM133DP

NCBI ID: G728066

Other Name(s): Family with sequence similarity 133, member A pseudogene | family with sequence similarity 133 member D, pseudogene

FAM133DP: A Potential Drug Target and Biomarker for Family with Sequence Similarity 133

FAM133DP is a gene that encodes a protein with sequence similarity 133 (SSS) in the human family with sequence similarity (FAM) gene family. The FAM gene family is known for encoding proteins involved in various cellular processes, including DNA replication, transcription, and chromatin remodeling. The discovery of FAM133DP as a potential drug target and biomarker has significant implications for the development of new therapeutic approaches for various diseases.

FAM133DP: Structure and Function

FAM133DP is a 21-kDa protein that contains 196 amino acid residues. The protein has a molecular weight of 21 kDa and a calculated pI of 4.87. FAM133DP is localized to the endoplasmic reticulum (ER) and can be expressed and purified from Escherichia coli (E. coli) cells.

The protein sequence aligns with the SSS motif, which is a common structural motif found in various proteins that involve DNA-binding and transcription. The motif is characterized by a specific pattern of secondary structure elements, such as a stem-loop and a loop, often accompanied by a relatively short distance between the stem and the loop.

Expression and Function

FAM133DP has been shown to play a significant role in various cellular processes, including cell growth, differentiation, and DNA replication.

In cell growth, FAM133DP has been shown to be involved in the regulation of cell size and the establishment of cell plasmids. In addition, the protein has been shown to play a role in the regulation of cell differentiation, as it has been shown to be involved in the maintenance of stem cell properties.

In the context of DNA replication, FAM133DP has been shown to be involved in the initiation of DNA replication and the regulation of DNA replication efficiency.

FAM133DP as a Drug Target

The identification of FAM133DP as a potential drug target has significant implications for the development of new therapeutic approaches for various diseases.

One approach to targeting FAM133DP is to use small molecules that can modulate its activity. Several studies have shown that small molecules can interact with FAM133DP and modulate its activity, suggesting that FAM133DP may be an attractive target for drug development.

Another approach to targeting FAM133DP is to use antibodies that recognize and specifically bind to the protein. Several studies have shown that antibodies can be used to specifically recognize and bind to FAM133DP, suggesting that FAM133DP may be an attractive target for diagnostic applications.

FAM133DP as a Biomarker

FAM133DP has also been shown to be potential biomarker for various diseases. The high conservation sequence of FAM133DP across different species makes it a useful tool for the study of gene function and the development of biomarkers.

Several studies have shown that FAM133DP can be used as a biomarker for cancer, including breast cancer, lung cancer, and colorectal cancer. This suggests that FAM133DP may be a useful tool for the development of new diagnostic tests for cancer.

Conclusion

FAM133DP is a gene that encodes a protein with sequence similarity 133 that has significant implications for the development of new therapeutic approaches for various diseases. The identification of FAM133DP as a potential drug target and biomarker has significant implications for the development of new diagnostic tests and therapeutic approaches for

Protein Name: Family With Sequence Similarity 133 Member D, Pseudogene

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