Target Name: IGFLR1
NCBI ID: G79713
Other Name(s): IGF-like family receptor 1 | IGF like family receptor 1 | IGFLR1 variant 1 | IGFR1_HUMAN | U2(RNU2) small nuclear RNA auxiliary factor 1-like 4 | IGF like family receptor 1, transcript variant 1 | Transmembrane protein 149 | U2AF1L4 | U2 small nuclear RNA auxiliary factor 1-like 4 | transmembrane protein 149 | TMEM149 | IGF-like family receptor 1 (isoform a)

IGF-1R: A Protein Interactions and Signaling Molecule

IGF-like family receptor 1 (IGFLR1) is a protein that is expressed in various tissues throughout the body. It is a member of the IGF-like family of proteins, which are characterized by the presence of an N-terminal extracellular domain, a transmembrane segment, and an C-terminal intracellular domain. IGF-like family receptors are involved in the regulation of cellular processes such as cell growth, differentiation, and survival.

One of the unique features of IGF-like family receptors is their ability to interact with multiple signaling pathways. They can be activated by a variety of ligands, including hormones, growth factors, and cytokines. This allows IGF-like family receptors to play important roles in the regulation of cellular processes that are relevant to a wide range of biological processes.

One of the most well-studied IGF-like family receptors is IGF-like receptor 1 (IGF-1R). IGF-1R is a transmembrane protein that is expressed in various tissues throughout the body, including muscle, fat, and bone. It is a potent receptor for the hormone insulin, which is produced by the pancreas and can stimulate the growth and metabolism of cells.

IGF-1R is involved in a wide range of cellular processes that are important for growth and development. It is a critical regulator of muscle growth and Maintenance of muscle mass, and it plays a role in the regulation of fat metabolism. IGF-1R signaling is also involved in the regulation of cellular processes that are relevant to diseases such as cancer, neurodegenerative diseases, and cardiovascular disease.

In addition to its role in cell growth and development, IGF-1R is also involved in the regulation of cellular processes that are important for maintenance of tissue homeostasis. It is a critical regulator of sodium and water homeostasis, which are essential for maintaining the proper structure and function of tissues.

IGF-1R is also involved in the regulation of cellular processes that are important for the regulation of pain and inflammation. It is a critical regulator of pain signaling, and it is involved in the regulation of the inflammatory response.

As a drug target, IGF-1R is an attractive target for the development of new treatments for a wide range of diseases. For example, IGF-1R has been shown to be involved in the regulation of a wide range of cellular processes that are important for cancer, neurodegenerative diseases, and cardiovascular disease.

In addition to its potential as a drug target, IGF-1R is also an attractive biomarker for the diagnosis and prognosis of various diseases. For example, IGF-1R has been shown to be involved in the regulation of cellular processes that are important for the development and progression of cancer. This makes IGF-1R an attractive biomarker for the diagnosis and prognosis of cancer.

In conclusion, IGF-like family receptor 1 (IGFLR1) is a protein that is involved in the regulation of a wide range of cellular processes that are important for growth and development, maintenance of tissue homeostasis, and the regulation of pain and inflammation. As A drug target and biomarker, IGF-1R is an attractive target for the development of new treatments for a wide range of diseases.

Protein Name: IGF Like Family Receptor 1

Functions: Probable cell membrane receptor for the IGF-like family proteins. Binds IGFL1 and IGFL3 with a higher affinity. May also bind IGFL2

More Common Targets

IGFN1 | IGH@ | IGHA1 | IGHA2 | IGHD | IGHD1-1 | IGHD1-14 | IGHD1-20 | IGHD1-26 | IGHD1-7 | IGHD2-15 | IGHD2-2 | IGHD2-21 | IGHD2-8 | IGHD3-10 | IGHD3-16 | IGHD3-22 | IGHD3-3 | IGHD3-9 | IGHD4-11 | IGHD4-17 | IGHD4-23 | IGHD4-4 | IGHD5-12 | IGHD5-18 | IGHD5-24 | IGHD5-5 | IGHD5OR15-5B | IGHD6-13 | IGHD6-19 | IGHD6-25 | IGHD6-6 | IGHD7-27 | IGHE | IGHEP1 | IGHEP2 | IGHG1 | IGHG2 | IGHG3 | IGHG4 | IGHGP | IGHJ1P | IGHJ2 | IGHJ2P | IGHJ3 | IGHJ3P | IGHJ4 | IGHJ5 | IGHJ6 | IGHM | IGHMBP2 | IGHV1-12 | IGHV1-14 | IGHV1-17 | IGHV1-18 | IGHV1-2 | IGHV1-24 | IGHV1-3 | IGHV1-45 | IGHV1-46 | IGHV1-58 | IGHV1-67 | IGHV1-68 | IGHV1-69 | IGHV1-69-2 | IGHV1-69D | IGHV1-8 | IGHV1OR15-1 | IGHV1OR15-2 | IGHV1OR15-5 | IGHV1OR15-9 | IGHV1OR21-1 | IGHV2-10 | IGHV2-26 | IGHV2-5 | IGHV2-70 | IGHV2-70D | IGHV2OR16-5 | IGHV3-11 | IGHV3-13 | IGHV3-15 | IGHV3-16 | IGHV3-19 | IGHV3-20 | IGHV3-21 | IGHV3-22 | IGHV3-23 | IGHV3-25 | IGHV3-29 | IGHV3-30 | IGHV3-30-2 | IGHV3-32 | IGHV3-33 | IGHV3-33-2 | IGHV3-36 | IGHV3-37 | IGHV3-38 | IGHV3-41 | IGHV3-42 | IGHV3-43