Target Name: STARD5
NCBI ID: G80765
Other Name(s): StARD5 | StAR related lipid transfer domain containing 5 | START domain-containing protein 5 | MGC10327 | STARD5 variant 1 | START domain containing 5 | StAR related lipid transfer domain containing 5, transcript variant 1 | STAR5_HUMAN | StAR-related lipid transfer protein 5 | OTTHUMP00000190848 | StAR-related lipid transfer (START) domain containing 5

STARD5: A Potential Drug Target and Biomarker

Introduction

Stroke is a leading cause of morbidity and mortality worldwide, affecting over 170 million people each year. The underlying cause of stroke is the disruption of blood flow to the brain, which can result in a range of devastating effects, including paralysis, loss of vision , and even death. Despite advances in stroke treatment, the survival rate remains poor, and the long-term effects of stroke can be devastating. Therefore, there is a need for new treatments and better diagnostic tools to improve outcomes.

STARD5 is a potential drug target and biomarker that has been identified as a promising candidate for stroke treatment. In this article, we will discuss the biology of stroke, the development of STARD5 as a drug target, and its potential as a biomarker for stroke.

The Biology of Stroke

Stroke is a complex disease that involves the disruption of blood flow to the brain. This disruption can occur due to a blockage of blood vessels, called ischemia, or the rupture of blood vessels, called hemorrhage. Ischemia is the most common cause of stroke, accounting for approximately 60% of cases, while hemorrhage accounts for the remaining 40%.

Stroke is a medical emergency and requires treatment as soon as possible. The severity of stroke can vary from mild to severe, with the latter being the most

Protein Name: StAR Related Lipid Transfer Domain Containing 5

Functions: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols (By similarity)

More Common Targets

STARD6 | STARD7 | STARD7-AS1 | STARD8 | STARD9 | STARP1 | STAT1 | STAT2 | STAT3 | STAT4 | STAT4-AS1 | STAT5 | STAT5A | STAT5B | STAT6 | STATH | STAU1 | STAU2 | STAU2-AS1 | STBD1 | STC1 | STC2 | STEAP1 | STEAP1B | STEAP2 | STEAP2-AS1 | STEAP3 | STEAP3-AS1 | STEAP4 | STEEP1 | Steroid 5-alpha-Reductase | Sterol O-acyltransferase (ACAT) | Sterol Regulatory Element-Binding Protein | STH | STIL | STIM1 | STIM2 | STIMATE | STIN2-VNTR | STING1 | STIP1 | STK10 | STK11 | STK11IP | STK16 | STK17A | STK17B | STK19 | STK24 | STK25 | STK26 | STK3 | STK31 | STK32A | STK32A-AS1 | STK32B | STK32C | STK33 | STK35 | STK36 | STK38 | STK38L | STK39 | STK4 | STK4-DT | STK40 | STKLD1 | STMN1 | STMN2 | STMN3 | STMN4 | STMND1 | STMP1 | STN1 | STOM | STOML1 | STOML2 | STOML3 | STON1 | STON1-GTF2A1L | STON2 | Store-operating calcium channel channels | STOX1 | STOX2 | STPG1 | STPG2 | STPG3 | STPG3-AS1 | STPG4 | STRA6 | STRA6LP | STRA8 | STRADA | STRADB | STRAP | STRBP | STRC | STRCP1 | STRIP1 | STRIP2