CASP5: A Key Protein in Cell Death and Cellular Processes (G838)

Target Name: CASP5

NCBI ID: G838

CASP5: A Key Protein in Cell Death and Cellular Processes

CASP5, or caspase-5 subunit p10, is a protein that is expressed in a variety of cell types and is involved in the process of cell death, specifically apoptosis. It is a key player in the caspase-dependent apoptosis (caspase -dependent cell death) pathway, which is a highly regulated process that is involved in the elimination of damaged or dysfunctional cells.

CASP5 is a member of the caspase family, which includes proteins that are involved in cell death by apoptosis. The caspases are a group of proteins that are known to promote the formation of a pro-apoptotic protein complex, which can trigger the caspase-dependent cell death pathway.

CASP5 is a subunit of the caspase-5 enzyme, which is a key component of the caspase-dependent cell death pathway. The caspase-5 enzyme is composed of two subunits, the alpha subunit and the beta subunit, which are responsible for the formation of the pro-apoptotic protein complex.

The caspase-5 subunit p10 is a 120-amino acid protein that is located within the alpha subunit of the caspase-5 enzyme. It is involved in the formation of the pro-apoptotic protein complex, which is composed of the protein Bax and the polyprotein p200.

The role of CASP5 in cell death is multifaceted and complex.CASP5 is involved in the formation of the pro-apoptotic protein complex, which is the first step in the caspase-dependent cell death pathway. It is also involved in the regulation of the pro -apoptotic protein complex, which is required for the formation of the irreversible damage that is necessary for cell death.

In addition to its role in the caspase-dependent cell death pathway, CASP5 is also involved in the regulation of cellular processes that are important for cell survival. It is involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs, and it is also involved in the regulation of cell migration, which is the process by which cells move from their place of origin to their final destination.

CASP5 is a protein that is expressed in a variety of cell types, including neurons, macrophages, and dendritic cells. It is also a potential drug target, and several studies have investigated its potential as a therapeutic agent for a variety of diseases, including cancer , neurodegenerative diseases, and cardiovascular disease.

One of the most promising applications for CASP5 as a drug target is its potential to treat cancer. Cancer is a disease that is characterized by the formation of tumors, which are collections of cells that have rebelled and rapidly proliferated. CASP5 is

Protein Name: Caspase 5

Functions: Thiol protease that acts as a mediator of programmed cell death (PubMed:29898893, PubMed:28314590). Initiates pyroptosis, a programmed lytic cell death pathway through cleavage of Gasdermin-D (GSDMD): cleavage releases the N-terminal gasdermin moiety (Gasdermin-D, N-terminal) that binds to membranes and forms pores, triggering pyroptosis (PubMed:29898893). During non-canonical inflammasome activation, cuts CGAS and may play a role in the regulation of antiviral innate immune activation (PubMed:28314590)

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