CDC124: A Cell Surface Glycoprotein Involved in Immune Response and Cancer Progression

Target Name: CCDC124

NCBI ID: G115098

CDC124: A Cell Surface Glycoprotein Involved in Immune Response and Cancer Progression

CCDC124 (CC124_HUMAN), also known as human CCR7, is a cell surface glycoprotein that is expressed in various tissues and cells throughout the body. It is a member of the CCR7 family, which includes several related proteins that play important roles in cell signaling and immune responses.

CDC124 is a 21-kDa protein that is expressed in various tissues, including the skin, lung, heart, liver, and pancreas. It is highly expressed in immune cells, including dendritic cells, macrophages, and natural killer cells (3 ). In addition, it is also expressed in cancer cells, including breast, ovarian, and prostate cancer cells.

CDC124 is involved in several different cellular processes, including cell adhesion, migration, and survival. It is a critical regulator of the immune response, as it helps to ensure that immune cells are able to migrate to and differentiate into various tissues ( 6). It is also involved in the regulation of cell growth and differentiation, as well as in the development and progression of cancer.

CDC124 is a potential drug target, as it has been shown to be involved in several different signaling pathways that are involved in cancer progression. For example, studies have shown that high levels of CDC124 are associated with poor prognosis in breast cancer patients , and that inhibition of its activity has been shown to be effective in treating this type of cancer. In addition, studies have also shown that CDC124 is involved in the development and progression of ovarian cancer, and that inhibition of its activity has has been shown to be effective in treating this type of cancer.

CDC124 is also a potential biomarker for cancer, as its levels have been shown to be elevated in a variety of cancer types, including breast, ovarian, and prostate cancer. In addition, studies have also shown that CDC124 can be used as a predictive marker for cancer outcomes, as high levels of CDC124 are associated with poor prognosis in cancer patients.

In conclusion, CDC124 is a cell surface glycoprotein that is involved in several different cellular processes that are important for cell signaling and immune responses. It is expressed in various tissues and cells throughout the body and is a potential drug target and biomarker for cancer. Further research is needed to fully understand the role of CDC124 in cancer progression and treatment.

Protein Name: Coiled-coil Domain Containing 124

Functions: Required for proper progression of late cytokinetic stages

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