Target Name: CCDC15
NCBI ID: G80071
Other Name(s): CCD15_HUMAN | Coiled-coil domain-containing protein 15 | Coiled-coil domain containing 15 | FLJ13215 | coiled-coil domain containing 15

CDC15: Key Protein in Immune and Inflammatory Response

CCDC15 (Complement Component 15) is a protein that is expressed in many different tissues throughout the body. It is a key component of the complement system, which is a group of proteins that work together to help the immune system fight off infections. CCDC15 is made up of 25 different amino acids and has a calculated molecular weight of 21 kDa.

One of the key functions of CCDC15 is its role in the immune response. It is a component of the complement component 15 (CC15), which is a group of proteins that help to mark and tag invading particles so that they can be recognized by the immune system. CCDC15 is also involved in the formation of the immunological memory, which is the ability of the immune system to remember an invading pathogen and respond quickly and effectively when it is encountered again.

In addition to its role in the immune system, CCDC15 is also involved in the regulation of inflammation. It is a component of the inflammasome, which is a group of proteins that help to generate the pro-inflammatory cytokine interleukin-1 (IL-1). Once activated, the inflammasome can cause a variety of cellular responses, including the production of pro-inflammatory cytokines and the formation of immune cells.

CDC15 is also involved in the regulation of cell death. It is a component of the apoptosis-associated caspase (APC), which is a group of proteins that help to regulate cell death. When the APC is activated, it can cause a variety of cellular responses, including the production of pro-inflammatory cytokines and the formation of immune cells.

In addition to its role in the immune and inflammatory responses, CCDC15 is also involved in the regulation of cell adhesion. It is a component of the cadherin protein, which is a transmembrane protein that helps to regulate cell-cell adhesion. CCDC15 is involved in the formation of tight junctions, which are a type of cell-cell adhesion that helps to maintain the integrity of tissues.

CDC15 is also involved in the regulation of cell signaling. It is a component of the T-cell signaling pathway, which is a group of signaling pathways that help to regulate the growth and differentiation of T cells. CCDC15 is involved in the formation of the T-cell receptor (TCR), which is the protein that T cells use to recognize foreign antigens.

In conclusion, CCDC15 is a protein that is involved in a variety of cellular processes throughout the body. Its role in the immune and inflammatory responses, as well as its involvement in cell adhesion and signaling, make it an attractive drug target for researchers. Further research is needed to fully understand the functions of CCDC15 and its potential as a drug.

Protein Name: Coiled-coil Domain Containing 15

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