CCDC71: A Potential Drug Target and Biomarker (G64925)

Target Name: CCDC71

NCBI ID: G64925

CCDC71: A Potential Drug Target and Biomarker

CDC71 is a protein that is expressed in various tissues of the human body, including the brain, heart, and kidneys. It is a member of the coat-neuron gene family and is localized to the endoplasmic reticulum. CDC71 has been identified as a potential drug target and biomarker due to its unique structure and subcellular localization.

Structure and Localization

CDC71 is a protein that consists of a single transmembrane domain and a cytoplasmic tail. It has a characteristic coiled-coil structure that is composed of four伪-helices. The coiled-coil region is responsible for the protein's unique localization to the endoplasmic reticulum, where it is involved in the regulation of protein synthesis and degradation.

CDC71 is a cytoplasmic protein, which means that it is localized to the cytoplasm of the cell, and its localization to the endoplasmic reticulum suggests that it may be involved in the regulation of protein synthesis and degradation in the cell. However, further studies are needed to confirm this hypothesis.

CDC71 and Protein Synthesis

CDC71 is known to be involved in the regulation of protein synthesis and degradation in the cell. This is evident from its coiled-coil structure, which is thought to play a role in the regulation of the endoplasmic reticulum. The coiled-coil region of CDC71 is able to interact with various protein partners, including the heat shock protein (HSP)70, which is known to play a role in the regulation of protein synthesis and degradation.

Studies have shown that HSP70 can interact with the cytoplasmic region of CDC71 and that this interaction may be involved in the regulation of protein synthesis and degradation. This suggests that CDC71 may be involved in the regulation of protein synthesis and degradation in the cell, and that it may be a potential drug target.

CDC71 and Biomarkers

CDC71 has also been identified as a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. This is because of its localization to the endoplasmic reticulum, which suggests that it may be involved in the regulation of protein synthesis and degradation in the cell.

Studies have shown that CDC71 is expressed in various tissues of the human body, including the brain, heart, and kidneys, and that it is involved in the regulation of protein synthesis and degradation in these tissues. This suggests that CDC71 may be a potential biomarker for various diseases.

CDC71 and Drug Targets

CDC71 is also a potential drug target due to its unique structure and subcellular localization. The coiled-coil structure of CDC71 makes it a potential target for small molecules, such as drugs, that can modulate its activity.

Studies have shown that various small molecules have been shown to interact with the coiled-coil region of CDC71 and that this interaction may be involved in the regulation of protein synthesis and degradation in the cell. This suggests that CDC71 may be a potential drug target and that small molecules may be effective in modulating its activity.

Conclusion

In conclusion, CDC71 is a protein that is expressed in various tissues of the human body and has been identified as a potential drug target and biomarker. Its characteristic coiled-coil structure and subcellular localization make it a potential target for small molecules that can modulate its activity. Further studies are needed to confirm this hypothesis and to determine the full extent of CDC71's involvement in the regulation of protein synthesis and degradation in the cell.

Protein Name: Coiled-coil Domain Containing 71

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