Target Name: CCL4L2
NCBI ID: G9560
Other Name(s): AT744.2 | C-C motif chemokine 4-like | C-C motif chemokine ligand 4 like 2, transcript variant CCL4L2c | macrophage inflammatory protein 1-beta | C-C motif chemokine 4-like (isoform 7) | C-C motif chemokine 4-like (isoform 3) | Small inducible cytokine A4-like | CCL4L2 variant CCL4L2c | Lymphocyte activation gene 1 protein | LAG-1 | chemokine (C-C motif) ligand 4-like 2 | C-C motif chemokine ligand 4 like 2, transcript variant CCL4L2f | CCL4L | Monocyte adherence-induced protein 5-alpha | MIP-1-beta | Macrophage inflammatory protein-1b2 | CC4L_HUMAN | Chemokine (C-C motif) ligand 4-like 2 | small inducible cytokine A4-like | Small-inducible cytokine A4-like | CCL4L2 variant CCL4L2f | SCYA4L | SCYQ4L2 | C-C motif chemokine ligand 4 like 2 | macrophage inflammatory protein-1b2 | monocyte adherence-induced protein 5-alpha | Macrophage inflammatory protein 1-beta

CCL4L2: A Protein Involved in Cell Signaling and Immune Regulation

CCL4L2 (AT744.2) is a protein that is expressed in various tissues of the body, including the lungs, heart, kidneys, and intestines. It is a member of the tight junction protein family, which plays a critical role in maintaining tissue barrier function. CCL4L2 is known for its ability to form tight junctions, which are specialized barriers that regulate the movement of ions and molecules into and out of cells.

Recent studies have identified CCL4L2 as a potential drug target for various diseases, including cancer, respiratory tract infections, and autoimmune disorders. Its role in these conditions makes it an attractive target for researchers to study and develop new treatments.

One of the key reasons for the interest in CCL4L2 is its ability to interact with multiple intracellular signaling pathways. CCL4L2 has been shown to play a role in several signaling pathways that are involved in cell growth, survival, and inflammation. For example, studies have shown that CCL4L2 can interact with the TGF-β pathway, a signaling pathway that is involved in cell growth and survival.

Additionally, CCL4L2 has been shown to be involved in the regulation of cellular immigration. This is important because the ability of cells to migrate is a critical factor in the development of many diseases, including cancer. CCL4L2 has been shown to play a role in the regulation of cell migration by controlling the movement of the protein ZEB2.

Another study has shown that CCL4L2 is involved in the regulation of inflammation. This is important because inflammation is a critical factor in the development of many diseases, including autoimmune disorders. CCL4L2 has been shown to play a role in the regulation of inflammation by controlling the movement of immune cells into the site of inflammation.

In conclusion, CCL4L2 is a protein that has been shown to play a critical role in several signaling pathways that are involved in cell growth, survival, and inflammation. Its potential as a drug target makes it an attractive target for researchers to study and develop new treatments for a variety of diseases. Further research is needed to fully understand the role of CCL4L2 in these conditions and to develop effective treatments.

Protein Name: C-C Motif Chemokine Ligand 4 Like 2

Functions: Chemokine that induces chemotaxis of cells expressing CCR5 or CCR1. Inhibits HIV replication in peripheral blood monocytes that express CCR5

More Common Targets

CCL5 | CCL7 | CCL8 | CCM2 | CCM2L | CCN1 | CCN2 | CCN3 | CCN4 | CCN5 | CCN6 | CCNA1 | CCNA2 | CCNB1 | CCNB1IP1 | CCNB2 | CCNB2P1 | CCNB3 | CCNC | CCND1 | CCND2 | CCND2-AS1 | CCND3 | CCNDBP1 | CCNE1 | CCNE2 | CCNF | CCNG1 | CCNG2 | CCNH | CCNI | CCNI2 | CCNJ | CCNJL | CCNK | CCNL1 | CCNL2 | CCNO | CCNP | CCNQ | CCNQP1 | CCNT1 | CCNT2 | CCNT2-AS1 | CCNT2P1 | CCNY | CCNYL1 | CCNYL2 | CCP110 | CCPG1 | CCR1 | CCR10 | CCR12P | CCR2 | CCR3 | CCR4 | CCR4-NOT transcription complex | CCR5 | CCR5AS | CCR6 | CCR7 | CCR8 | CCR9 | CCRL2 | CCS | CCSAP | CCSER1 | CCSER2 | CCT2 | CCT3 | CCT4 | CCT5 | CCT6A | CCT6B | CCT6P1 | CCT6P3 | CCT7 | CCT8 | CCT8L1P | CCT8L2 | CCT8P1 | CCZ1 | CCZ1B | CCZ1P-OR7E38P | CD101 | CD101-AS1 | CD109 | CD14 | CD151 | CD160 | CD163 | CD163L1 | CD164 | CD164L2 | CD177 | CD177P1 | CD180 | CD19 | CD1A | CD1B