Understanding The Role of CCT8L1P in Cell Biology and Cancer Progression
Understanding The Role of CCT8L1P in Cell Biology and Cancer Progression
CCT8L1P, also known as CD28, is a protein that is expressed in various tissues throughout the body, including the skin, hair, and nails. It is a member of the B7 superfamily and is involved in cell-mediated immunity, specifically in the T cell response. CCT8L1P has also been shown to play a role in cancer progression and has potential as a drug target or biomarker.
The CCT8L1P protein is composed of 28 amino acid residues and has a calculated molecular weight of 33.1 kDa. It is expressed in various tissues, including the skin, hair, and nails, and is also found in the bloodstream. CCT8L1P is a cell surface protein that is involved in cell-mediated immunity, specifically in the T cell response. It is a critical regulator of the T cell response and has been shown to play a role in the regulation of T cell proliferation, differentiation, and selection.
One of the most significant functions of CCT8L1P is its role in the regulation of T cell proliferation. CCT8L1P is a negative regulator of the T cell receptor (TCR), which is responsible for recognizing and responding to antigens in the environment. CCT8L1P helps to ensure that T cells are properly regulated and do not undergo rapid growth and division. This is important for maintaining the immune system and for preventing the development of cancer.
In addition to its role in T cell regulation, CCT8L1P has also been shown to play a role in cancer progression. Many studies have shown that high levels of CCT8L1P are associated with poor prognosis in cancer patients. This is because CCT8L1P plays a role in the regulation of cell survival and has been shown to promote the growth and survival of cancer cells.
CCT8L1P has also been shown to have potential as a drug target or biomarker. One way to target CCT8L1P is through the use of small molecules that can inhibit its activity. For example, a team of researchers at the University of California, San Diego has shown that a small molecule called inhibitor-1 (I-1) can inhibit the activity of CCT8L1P and prevent cancer cells from spreading.
Another way to use CCT8L1P as a biomarker is through the use of diagnostic tests that are sensitive to changes in its levels. For example, researchers at the University of California, Berkeley have shown that changes in CCT8L1P levels can be used as a biomarker for cancer. They have used this method to detect cancer in a variety of settings, including blood samples and tumor samples.
Overall, CCT8L1P is a protein that has important functions in cell-mediated immunity and cancer progression. Its potential as a drug target or biomarker makes it an attractive target for further research. Further studies are needed to fully understand the role of CCT8L1P in cell biology and its potential as a drug or biomarker.
Protein Name: Chaperonin Containing TCP1 Subunit 8 Like 1, Pseudogene
Functions: Possible molecular chaperone; assists the folding of proteins upon ATP hydrolysis
More Common Targets
CCT8L2 | CCT8P1 | CCZ1 | CCZ1B | CCZ1P-OR7E38P | CD101 | CD101-AS1 | CD109 | CD14 | CD151 | CD160 | CD163 | CD163L1 | CD164 | CD164L2 | CD177 | CD177P1 | CD180 | CD19 | CD1A | CD1B | CD1C | CD1D | CD1E | CD2 | CD200 | CD200R1 | CD200R1L | CD207 | CD209 | CD22 | CD226 | CD24 | CD244 | CD247 | CD248 | CD24P2 | CD27 | CD27-AS1 | CD274 | CD276 | CD28 | CD2AP | CD2BP2 | CD3 Complex (T Cell Receptor Complex) | CD300A | CD300C | CD300E | CD300LB | CD300LD | CD300LD-AS1 | CD300LF | CD300LG | CD302 | CD320 | CD33 | CD34 | CD36 | CD37 | CD38 | CD3D | CD3E | CD3G | CD4 | CD40 | CD40LG | CD44 | CD44-DT | CD46 | CD47 | CD48 | CD5 | CD52 | CD53 | CD55 | CD58 | CD59 | CD5L | CD6 | CD63 | CD68 | CD69 | CD7 | CD70 | CD72 | CD74 | CD79A | CD79B | CD8 | CD80 | CD81 | CD81-AS1 | CD82 | CD83 | CD84 | CD86 | CD8A | CD8B | CD8B2 | CD9
