CCDC77: A Protein Involved in Neurodegenerative Diseases and Normal Brain Development

Target Name: CCDC77

NCBI ID: G84318

CCDC77: A Protein Involved in Neurodegenerative Diseases and Normal Brain Development

CCDC77 (Clinical Data Documentation Command Center) 77 is a protein that is expressed in various tissues and organs, including the brain, spinal cord, and peripheral nerves. It is a member of the superfamily of immediate-early genes (SEG) and is characterized by the presence of a unique N-terminal signal peptide and a C-terminal transmembrane domain.

CCDC77 is involved in the regulation of neural cell survival and proliferation. It has been shown to play a role in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

One of the unique aspects of CCDC77 is its ability to form a complex with other proteins, including the neurotransmitter dopamine. This interaction between CCDC77 and dopamine has been shown to play a role in the regulation of neural circuits and is a potential drug target for the treatment of neurodegenerative diseases.

In addition to its role in neurodegenerative diseases, CCDC77 has also been shown to be involved in the regulation of normal brain development and function. It has been shown to play a role in the development and maintenance of the nervous system, and is involved in the regulation of neurotransmitter release and synaptic plasticity.

CCDC77 is also involved in the regulation of inflammation and immune response. It has been shown to play a role in the regulation of inflammatory responses and is involved in the development of neuroinflammation.

In conclusion, CCDC77 is a protein that has been shown to play a role in the development and progression of neurodegenerative diseases, as well as in the regulation of normal brain development and function. Its unique ability to form a complex with other proteins, including dopamine, makes it a potential drug target for the treatment of neurodegenerative diseases. Further research is needed to fully understand the role of CCDC77 in neural biology and the development of neurodegenerative diseases.

Protein Name: Coiled-coil Domain Containing 77

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