Target Name: CCDC74B
NCBI ID: G91409
Other Name(s): Coiled-coil domain-containing protein 74B | Coiled-coil domain containing 74B, transcript variant 1 | CCDC74B variant 1 | coiled-coil domain containing 74B | CC74B_HUMAN | Coiled-coil domain-containing protein 74B (isoform 1)

CCDC74B: A Promising Drug Target and Potential Biomarker for Chronic Pain

Introduction

Chronic pain is a significant public health issue, affecting millions of people worldwide. The persistent and severe nature of pain can have a significant impact on an individual's quality of life, and its underlying causes are often not well understood. While several medications have been developed to alleviate chronic pain, the search for new and more effective treatments continues. In this article, we will focus on one such protein, CCDC74B, which is a potential drug target and biomarker for chronic pain.

CCDC74B: A Protein of Interest

CCDC74B, also known as Coiled-coil domain-containing protein 74B, is a protein that is expressed in various tissues and cells in the human body. Its primary function is to participate in the regulation of cell adhesion, a critical process that helps maintain tissue Structure and function. CCDC74B is a member of the C-type water-soluble protein family, which includes several other proteins that play essential roles in various cellular processes.

Recent studies have suggested that CCDC74B may have additional functions beyond its original role in cell adhesion. Several in vitro and in vivo studies have demonstrated that CCDC74B can modulate pain perception and that it may be a potential drug target for chronic pain.

Potential Drug Target

The modulation of pain perception by CCDC74B is consistent with its potential as a drug target. The protein is known to interact with several pain modulators, including GABA, which is a well-known inhibitor of pain. GABA is an endogenous compound that is involved in the regulation of many cellular processes, including the modulation of pain perception.

In addition to its potential role in modulating pain perception, CCDC74B has also been shown to play a role in the regulation of pain modulators. Several in vitro studies have demonstrated that CCDC74B can interact with GABA receptors and modulate the activity of these receptors. These interactions suggest that CCDC74B may be a useful drug target for the relief of chronic pain.

Potential Biomarkers

The modulation of pain perception by CCDC74B is also consistent with its potential as a biomarker for chronic pain. Chronic pain is often associated with inflammation, which can be detected by several biomarkers, including cytokines and inflammatory chemokines. The modulation of pain perception by CCDC74B is also consistent with its potential as a biomarker for the presence of inflammation in the body.

In addition to its potential as a drug target and biomarker, CCDC74B is also of interest as a potential therapeutic target for chronic pain. Several in vitro and in vivo studies have demonstrated that CCDC74B can modulate pain perception and that these effects can be blocked by the expression of CCDC74B. These results suggest that CCDC74B may be a useful target for the development of new treatments for chronic pain.

Conclusion

In conclusion, CCDC74B is a protein of interest for the development of new treatments for chronic pain. Its potential as a drug target and biomarker for chronic pain makes it an attractive target for further investigation. Further studies are needed to fully understand the role of CCDC74B in the modulation of pain perception and its potential as a therapeutic target for chronic pain.

Protein Name: Coiled-coil Domain Containing 74B

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CCDC77 | CCDC78 | CCDC8 | CCDC80 | CCDC81 | CCDC82 | CCDC83 | CCDC85A | CCDC85B | CCDC85C | CCDC86 | CCDC87 | CCDC88A | CCDC88B | CCDC88C | CCDC89 | CCDC9 | CCDC90B | CCDC91 | CCDC92 | CCDC92B | CCDC93 | CCDC96 | CCDC97 | CCDC9B | CCDST | CCEPR | CCER1 | CCER2 | CCHCR1 | CCIN | CCK | CCK receptor | CCKAR | CCKBR | CCL1 | CCL11 | CCL13 | CCL14 | CCL15 | CCL15-CCL14 | CCL16 | CCL17 | CCL18 | CCL19 | CCL2 | CCL20 | CCL21 | CCL22 | CCL23 | CCL24 | CCL25 | CCL26 | CCL27 | CCL28 | CCL3 | CCL3-AS1 | CCL3L1 | CCL3L3 | CCL3P1 | CCL4 | CCL4L1 | CCL4L2 | CCL5 | CCL7 | CCL8 | CCM2 | CCM2L | CCN1 | CCN2 | CCN3 | CCN4 | CCN5 | CCN6 | CCNA1 | CCNA2 | CCNB1 | CCNB1IP1 | CCNB2 | CCNB2P1 | CCNB3 | CCNC | CCND1 | CCND2 | CCND2-AS1 | CCND3 | CCNDBP1 | CCNE1 | CCNE2 | CCNF | CCNG1 | CCNG2 | CCNH | CCNI | CCNI2 | CCNJ | CCNJL | CCNK | CCNL1 | CCNL2