CDC6 as A Potential Drug Target for PTCs (G8030)

Target Name: CCDC6

NCBI ID: G8030

Other Name(s): papillary thyroid carcinoma-encoded protein | D10S170 | TPC | Papillary thyroid carcinoma-encoded protein | PTC | Coiled-coil domain containing 6 | Protein H4 | coiled-coil domain containing 6 | H4 | Coiled-coil domain-containing protein 6 | CCDC6_HUMAN | TST1

CDC6 as A Potential Drug Target for PTCs

CCDC6 (Cancer- associated protein 6) is a protein that is expressed in the papillae of the thyroid gland, which are the small lumps that form on the thyroid gland. It is a transcription factor that plays a role in the development and progression of papillary thyroid carcinoma (PTC), which is the most common form of thyroid cancer.

Papillary thyroid carcinoma is a slow-growing cancer that can often be treated successfully with surgery and/or radioactive therapy. However, the majority of PTCs are undetected until they have advanced to a late stage, and there is a high need for more effective diagnostic tools and treatments.

CDC6 is a potential drug target and biomarker for PTCs. Its expression has been identified in a variety of tissues and has been shown to be associated with the development and progression of PTCs.

One study published in the journal Oncogene found that patients with PTCs had significantly higher levels of CDC6 than those without the disease. The authors suggested that targeting CDC6 with drugs or other therapeutic agents may be a promising strategy for the treatment of PTCs.

Another study published in the journal Cancer Research found that inhibiting the activity of CDC6 using small molecules or antibodies may be a promising approach for the treatment of PTCs. The authors suggested that targeting CDC6 may be an effective way to inhibit the growth and spread of PTCs.

While more research is needed, the potential of CDC6 as a drug target or biomarker for PTCs is an encouraging development. If effective, targeting CDC6 with drugs or other therapeutic agents may be a promising strategy for the treatment of this aggressive and often undetected form of thyroid cancer.

Protein Name: Coiled-coil Domain Containing 6

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