CDCC42: A Protein Regulating Cell Adhesion, Migration and More

Target Name: CCDC42

NCBI ID: G146849

CDCC42: A Protein Regulating Cell Adhesion, Migration and More

CCDC42 (CCDC42A) is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidney. It is a member of the C-typeWater/Protein-Protein (WPP) domain family, which is characterized by the presence of a single helix of amino acids that forms a尾-sheet.

CDC42 is known for its role in the regulation of cell adhesion and migration. It is a key regulator of tight junctions, which are specialized junctions that form between cells and help to maintain tissue structure and function. tight junctions are critical for the proper functioning of Various physiological processes in the body, including the regulation of ion and solute transport, as well as the maintenance of cellular order and the regulation of cell-cell interactions.

In addition to its role in tight junction regulation, CDC42 is also involved in the regulation of cell survival and proliferation. It has been shown to play a role in the regulation of cell cycle progression, and is thought to influence the G1/S transition that occurs at the end of the cell cycle.

CDC42 is also involved in the regulation of cell signaling pathways. It has been shown to play a role in the regulation of T cell signaling, and is thought to influence the development and maintenance of T cell memory.

CDC42 is also a potential drug target in the development of various diseases. For example, some studies have suggested that CDC42 may be a potential therapeutic target for the treatment of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. This is because the regulation of CDC42 by its downstream targets is thought to be disrupted in these diseases, and targeting the regulation of CDC42 may be a way to treat these conditions.

Another potential application of CDC42 as a drug target is the treatment of cancer. The regulation of CDC42 by its downstream targets is thought to be disrupted in many types of cancer, and targeting the regulation of CDC42 may be a way to treat these conditions.

In conclusion, CDC42 is a protein that is involved in a variety of physiological processes in the body. Its regulation of cell adhesion and migration, as well as its role in the regulation of cell cycle progression and signaling pathways, makes it a potential drug target in the development of various diseases. Further research is needed to fully understand the regulation of CDC42 and its potential as a therapeutic target.

Protein Name: Coiled-coil Domain Containing 42

Functions: Required for sperm development

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