CCDC18-AS1: A Potential Drug Target and Biomarker (G100131564)

Target Name: CCDC18-AS1

NCBI ID: G100131564

Other Name(s): CCDC18 antisense RNA 1

CCDC18-AS1: A Potential Drug Target and Biomarker

CDC18-AS1 is a protein that is expressed in various tissues of the body, including the lungs, heart, kidneys, and intestines. It is a member of the CCDC gene family, which is known for producing proteins that play a critical role in cell signaling and inflammation. One of the functions of CDC18-AS1 is to regulate the production of pro-inflammatory cytokines, which can contribute to the development of various diseases, including cancer.

CDC18-AS1 Interacts with Other Proteins

CDC18-AS1 has been shown to interact with several other proteins, including but not limited to:

1. NF-kappa-B2: This is a transcription factor that plays a critical role in cell signaling and inflammation. CDC18-AS1 has been shown to physically interact with NF-kappa-B2 and regulate its activity.
2. NF-kappa-B3: This is another transcription factor that is involved in cell signaling and inflammation. It is known to interact with CDC18-AS1 and regulate its activity.
3. TGF-β1: This is a transcription factor that is involved in cell signaling and growth. It is known to interact with CDC18-AS1 and regulate its activity.
4. Platelet-derived growth factor (PDGF): This is a cytokine that can stimulate the growth and differentiation of various cell types. It is known to interact with CDC18-AS1 and regulate its activity.

CDC18-AS1 Regulates Pro-Inflammatory Cytokine Production

CDC18-AS1 has been shown to regulate the production of pro-inflammatory cytokines, which are important mediators of inflammation. These cytokines include but are not limited to:

1. TNF-伪: This is a cytokine that is involved in inflammation and immune responses. It is known to be regulated by CDC18-AS1.
2. IL-1尾: This is a cytokine that is involved in inflammation and immune responses. It is known to be regulated by CDC18-AS1.
3. IL-6: This is a cytokine that is involved in inflammation and immune responses. It is known to be regulated by CDC18-AS1.
4. GIFT: This is a cytokine that is involved in inflammation and immune responses. It is known to be regulated by CDC18-AS1.
5. HIF1伪: This is a transcription factor that is involved in the regulation of inflammation and cellular responses to stress. It is known to be regulated by CDC18-AS1.

CDC18-AS1 as a Potential Drug Target

CDC18-AS1 has been shown to play a critical role in the regulation of pro-inflammatory cytokine production, which can contribute to the development of various diseases, including cancer. Therefore, targeting CDC18-AS1 may be a promising strategy for the development of new treatments for these diseases.

One potential approach to targeting CDC18-AS1 is to use small molecules or antibodies that can inhibit its activity. For example, small molecules that inhibit the activity of CDC18-AS1 have been shown to be effective in treating various diseases, including cancer. Similarly, antibodies that recognize and bind to CDC18-AS1 have been shown to be effective in treating various diseases, including cancer.

Conclusion

In conclusion, CDC18-AS1 is a protein that plays a critical role in the regulation of pro-inflammatory cytokine production, which can contribute to the development of various diseases. Therefore, targeting CDC18-AS1 with small molecules or antibodies may be a promising strategy for the development of new treatments for these diseases. Further research is needed to fully understand the role of CDC18-AS1 and to develop effective treatments.

Protein Name: CCDC18 Antisense RNA 1

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